Rac

(Difference between revisions)

Revision as of 12:39, 25 August 2019

Human Rac1 (magenta) complex with YpkA (cyan), GDP and Mg+2 ion (green) (PDB code 2h7v)

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Updated on 25-August-2019

↑ Asahara S, Shibutani Y, Teruyama K, Inoue HY, Kawada Y, Etoh H, Matsuda T, Kimura-Koyanagi M, Hashimoto N, Sakahara M, Fujimoto W, Takahashi H, Ueda S, Hosooka T, Satoh T, Inoue H, Matsumoto M, Aiba A, Kasuga M, Kido Y. Ras-related C3 botulinum toxin substrate 1 (RAC1) regulates glucose-stimulated insulin secretion via modulation of F-actin. Diabetologia. 2013 May;56(5):1088-97. doi: 10.1007/s00125-013-2849-5. Epub 2013, Feb 15. PMID:23412604 doi:http://dx.doi.org/10.1007/s00125-013-2849-5
↑ Prehna G, Ivanov MI, Bliska JB, Stebbins CE. Yersinia virulence depends on mimicry of host Rho-family nucleotide dissociation inhibitors. Cell. 2006 Sep 8;126(5):869-80. PMID:16959567 doi:10.1016/j.cell.2006.06.056

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 == Structural highlights ==
-The interactions between Rac1 and YpkA are via <scene name='75/752232/Cv/7'>switch I and switch II of Rac1 and a helical portion of the protein kinase YpkA</scene><ref>PMID:16959567</ref>. <scene name='75/752232/Cv/6'>GDP binding site on Rac1</scene>.
+The interactions between Rac1 and YpkA are via <scene name='75/752232/Cv/8'>switch I and switch II of Rac1 and a helical portion of the protein kinase YpkA</scene><ref>PMID:16959567</ref>. <scene name='75/752232/Cv/9'>GDP binding site on Rac1</scene>.
 </StructureSection>