6pjj
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Human PRPF4B bound to benzothiophene inhibitor 224== | |
| - | + | <StructureSection load='6pjj' size='340' side='right'caption='[[6pjj]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6pjj]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PJJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OCJ:4-(5-{[(3-aminophenyl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide'>OCJ</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | [[ | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> |
| - | [[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pjj OCA], [http://pdbe.org/6pjj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pjj RCSB], [http://www.ebi.ac.uk/pdbsum/6pjj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pjj ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/PRP4B_HUMAN PRP4B_HUMAN]] Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Arruda, P]] | [[Category: Arruda, P]] | ||
| - | [[Category: Structural Genomics Consortium (Sgc)]] | ||
| - | [[Category: Santiago, A.S]] | ||
| - | [[Category: Sriranganadane, D]] | ||
[[Category: Azevedo, H]] | [[Category: Azevedo, H]] | ||
| + | [[Category: Counago, R M]] | ||
| + | [[Category: Elkins, J M]] | ||
| + | [[Category: Fala, A M]] | ||
| + | [[Category: Godoi, P H.C]] | ||
| + | [[Category: Guimaraes, C R.W]] | ||
[[Category: Mascarello, A]] | [[Category: Mascarello, A]] | ||
| - | [[Category: | + | [[Category: Ramos, P Z]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: | + | [[Category: Santiago, A S]] |
| + | [[Category: Segretti, N]] | ||
| + | [[Category: Sriranganadane, D]] | ||
| + | [[Category: Serine/threonine-protein kinase prp4 homolog]] | ||
| + | [[Category: Sgc]] | ||
| + | [[Category: Splicing kinase prpf4b]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 15:33, 28 August 2019
Human PRPF4B bound to benzothiophene inhibitor 224
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Categories: Large Structures | Non-specific serine/threonine protein kinase | Arruda, P | Azevedo, H | Counago, R M | Elkins, J M | Fala, A M | Godoi, P H.C | Guimaraes, C R.W | Mascarello, A | Ramos, P Z | Structural genomic | Santiago, A S | Segretti, N | Sriranganadane, D | Serine/threonine-protein kinase prp4 homolog | Sgc | Splicing kinase prpf4b | Transferase | Transferase-transferase inhibitor complex
