6qnn
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==CLATHRIN HEAVY CHAIN N-TERMINAL DOMAIN BOUND TO GTSE1 LIDL MOTIF== | |
| - | + | <StructureSection load='6qnn' size='340' side='right'caption='[[6qnn]], [[Resolution|resolution]] 2.03Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6qnn]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QNN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QNN FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qnn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qnn OCA], [http://pdbe.org/6qnn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qnn RCSB], [http://www.ebi.ac.uk/pdbsum/6qnn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qnn ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/CLH1_HUMAN CLH1_HUMAN]] Translocation renal cell carcinoma;Inflammatory myofibroblastic tumor. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CLH1_HUMAN CLH1_HUMAN]] Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. [[http://www.uniprot.org/uniprot/GTSE1_HUMAN GTSE1_HUMAN]] May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Lin, Y]] | ||
| + | [[Category: Porfetye, A T]] | ||
| + | [[Category: Vetter, I R]] | ||
| + | [[Category: Beta-propeller]] | ||
| + | [[Category: Cell cycle]] | ||
| + | [[Category: Clathrin-box]] | ||
| + | [[Category: Lidl-motif]] | ||
Revision as of 15:35, 28 August 2019
CLATHRIN HEAVY CHAIN N-TERMINAL DOMAIN BOUND TO GTSE1 LIDL MOTIF
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