6r3f

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'''Unreleased structure'''
 
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The entry 6r3f is ON HOLD until Paper Publication
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==Aspergillus niger ferulic acid decarboxylase (Fdc) E282Q variant in complex with the covalent adduct formed between prFMN cofactor and cinnamic acid (Int2)==
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<StructureSection load='6r3f' size='340' side='right'caption='[[6r3f]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
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Authors: Bailey, S.S., Leys, D.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6r3f]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R3F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6R3F FirstGlance]. <br>
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Description: Aspergillus niger ferulic acid decarboxylase (Fdc) E282Q variant in complex with the covalent adduct formed between prFMN cofactor and cinnamic acid (Int2)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=JQK:[(2~{R},3~{S},4~{S})-2,3,4-tris(oxidanyl)-5-[(16~{R})-11,12,14,14-tetramethyl-5-oxidanyl-3-oxidanylidene-16-(2-phenylethyl)-1,4,6,8-tetrazatetracyclo[7.7.1.0^{2,7}.0^{13,17}]heptadeca-2(7),5,9(17),10,12-pentaen-8-yl]pentyl]+dihydrogen+phosphate'>JQK</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenacrylate_decarboxylase Phenacrylate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.102 4.1.1.102] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6r3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r3f OCA], [http://pdbe.org/6r3f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6r3f RCSB], [http://www.ebi.ac.uk/pdbsum/6r3f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6r3f ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/FDC1_ASPNC FDC1_ASPNC]] Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites.[HAMAP-Rule:MF_03196]<ref>PMID:26083754</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Phenacrylate decarboxylase]]
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[[Category: Bailey, S S]]
[[Category: Leys, D]]
[[Category: Leys, D]]
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[[Category: Bailey, S.S]]
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[[Category: Lyase]]
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[[Category: Prfmn binding]]
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[[Category: Ubid]]

Revision as of 15:38, 28 August 2019

Aspergillus niger ferulic acid decarboxylase (Fdc) E282Q variant in complex with the covalent adduct formed between prFMN cofactor and cinnamic acid (Int2)

PDB ID 6r3f

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