3zif
From Proteopedia
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==Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly== | ==Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly== | ||
| - | <StructureSection load='3zif' size='340' side='right' caption='[[3zif]], [[Resolution|resolution]] 4.50Å' scene=''> | + | <StructureSection load='3zif' size='340' side='right'caption='[[3zif]], [[Resolution|resolution]] 4.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3zif]] is a 18 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovine_adenovirus_3 Bovine adenovirus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZIF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZIF FirstGlance]. <br> | <table><tr><td colspan='2'>[[3zif]] is a 18 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovine_adenovirus_3 Bovine adenovirus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZIF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZIF FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zif FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zif OCA], [http://pdbe.org/3zif PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zif RCSB], [http://www.ebi.ac.uk/pdbsum/3zif PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zif ProSAT]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zif FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zif OCA], [http://pdbe.org/3zif PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zif RCSB], [http://www.ebi.ac.uk/pdbsum/3zif PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zif ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | {{Large structure}} | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/CAPSH_ADEB3 CAPSH_ADEB3]] Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid. Assembled into trimeric units with the help of the chaperone shutoff protein. Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid. Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus (By similarity). | [[http://www.uniprot.org/uniprot/CAPSH_ADEB3 CAPSH_ADEB3]] Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid. Assembled into trimeric units with the help of the chaperone shutoff protein. Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid. Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus (By similarity). | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Bovine adenovirus 3]] | [[Category: Bovine adenovirus 3]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Cheng, L]] | [[Category: Cheng, L]] | ||
[[Category: Huang, X]] | [[Category: Huang, X]] | ||
Revision as of 16:33, 28 August 2019
Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly
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Categories: Bovine adenovirus 3 | Large Structures | Cheng, L | Huang, X | Ji, G | Li, X | Liu, H | Sun, F | Sun, W | Wang, Y | Xiong, W | Yang, C | Zhang, K | Zheng, C | Zhu, P | Assembly intermediate | Virus
