Interleukin-1 receptor-associated kinase

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**[[2nru]], [[2nry]], [[2oib]], [[2o8y]], [[4rmz]] – hIRAK4 kinase domain - human<br />
**[[2nru]], [[2nry]], [[2oib]], [[2o8y]], [[4rmz]] – hIRAK4 kinase domain - human<br />
**[[4u97]], [[4u9a]] - hIRAK4 kinase domain (mutant)<br />
**[[4u97]], [[4u9a]] - hIRAK4 kinase domain (mutant)<br />
-
**[[1wh4]] – mIRAK4 DEATH domain – mouse – NMR<br />
 
-
**[[2a9i]] - mIRAK4 DEATH domain<br />
 
**[[2oic]], [[4xs2]] - hIRAK4 kinase domain + staurosporine<br />
**[[2oic]], [[4xs2]] - hIRAK4 kinase domain + staurosporine<br />
-
**[[4y73]], [[4yo6]], [[4yp8]], [[4ztl]], [[4ztm]], [[4ztn]], [[5kx7]], [[5kx8]], [[5t1s]], [[5t1t]], [[5uiq]], [[5uir]], [[5uis]], [[5uit]], [[5uiu]], [[6f3d]], [[6f3e]], [[6f3g]], [[6f3i]] - hIRAK4 kinase domain + inhibitor<br />
+
**[[4y73]], [[4yo6]], [[4yp8]], [[4ztl]], [[4ztm]], [[4ztn]], [[5kx7]], [[5kx8]], [[5t1s]], [[5t1t]], [[5uiq]], [[5uir]], [[5uis]], [[5uit]], [[5uiu]], [[6f3d]], [[6f3e]], [[6f3g]], [[6f3i]], [[6n8g]], [[6o8u]], [[6o94]], [[6o95]], [[6o9d]] - hIRAK4 kinase domain + inhibitor<br />
-
**[[5w84]], [[5w85]], [[5k72]], [[5k75]], [[5k76]], [[5k7g]], [[5k7i]] - hIRAK4 residues 154-460 + inhibitor<br />
+
**[[5w84]], [[5w85]], [[5k72]], [[5k75]], [[5k76]], [[5k7g]], [[5k7i]], [[6ega]], [[6eg9]], [[6egd]], [[6ege]], [[6egf]] - hIRAK4 residues 154-460 + inhibitor<br />
**[[2oid]] - hIRAK4 kinase domain + AMPPNP<br />
**[[2oid]] - hIRAK4 kinase domain + AMPPNP<br />
**[[3mop]] - hIRAK4 DEATH domain + hIRAK2 DEATH domain + MYD88<br />
**[[3mop]] - hIRAK4 DEATH domain + hIRAK2 DEATH domain + MYD88<br />
 +
**[[1wh4]] – mIRAK4 DEATH domain – mouse – NMR<br />
 +
**[[2a9i]] - mIRAK4 DEATH domain<br />
}}
}}
== References ==
== References ==

Revision as of 09:56, 3 September 2019

Mouse IRAK4 death domain complex with Mn+2 ion , 2a9i

Drag the structure with the mouse to rotate

3D structures of IRAK4

Updated on 03-September-2019

References

  1. Cao Z, Henzel WJ, Gao X. IRAK: a kinase associated with the interleukin-1 receptor. Science. 1996 Feb 23;271(5252):1128-31. PMID:8599092

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Michal Harel, Alexander Berchansky, Jaime Prilusky

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