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6qsk

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'''Unreleased structure'''
 
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The entry 6qsk is ON HOLD
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==Crystal structure of a nucleotide sugar transporter with bound nucleotide monophosphate.==
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<StructureSection load='6qsk' size='340' side='right'caption='[[6qsk]], [[Resolution|resolution]] 3.39&Aring;' scene=''>
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Authors: Newstead, S., Parker, J.L.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6qsk]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QSK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QSK FirstGlance]. <br>
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Description: Crystal structure of a nucleotide sugar transporter with bound nucleotide monophosphate.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5oge|5oge]], [[5ogk|5ogk]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qsk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qsk OCA], [http://pdbe.org/6qsk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qsk RCSB], [http://www.ebi.ac.uk/pdbsum/6qsk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qsk ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/GMT1_YEAST GMT1_YEAST]] Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen. Defective copy causes severe glycosylation defect and abnormal retention of soluble endoplasmic reticulum proteins. Involved in vanadate sensitivity.<ref>PMID:10570930</ref> <ref>PMID:11067855</ref> <ref>PMID:12478588</ref> <ref>PMID:15494368</ref> <ref>PMID:2014241</ref> <ref>PMID:2137555</ref> <ref>PMID:7672592</ref> <ref>PMID:7877969</ref> <ref>PMID:8632002</ref> <ref>PMID:9184829</ref> <ref>PMID:9335583</ref> <ref>PMID:9395539</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Newstead, S]]
[[Category: Newstead, S]]
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[[Category: Parker, J.L]]
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[[Category: Parker, J L]]
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[[Category: Gdp-mannose transport]]
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[[Category: Glycosylation]]
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[[Category: Golgi transporter]]
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[[Category: Membrane protein]]
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[[Category: Slc35]]

Revision as of 10:38, 2 October 2019

Crystal structure of a nucleotide sugar transporter with bound nucleotide monophosphate.

PDB ID 6qsk

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