6nvm
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of 23S rRNA methyltransferase ErmE== | |
| - | + | <StructureSection load='6nvm' size='340' side='right'caption='[[6nvm]], [[Resolution|resolution]] 1.75Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6nvm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NVM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NVM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/23S_rRNA_(adenine(2085)-N(6))-dimethyltransferase 23S rRNA (adenine(2085)-N(6))-dimethyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.184 2.1.1.184] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nvm OCA], [http://pdbe.org/6nvm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nvm RCSB], [http://www.ebi.ac.uk/pdbsum/6nvm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nvm ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ERME_SACEN ERME_SACEN]] This protein produces a dimethylation of the adenine residue at position 2085 in 23S rRNA, resulting in reduced affinity between ribosomes and macrolide-lincosamide-streptogramin B antibiotics. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Selmer, M]] | ||
| + | [[Category: Stsiapanava, A]] | ||
| + | [[Category: Erme]] | ||
| + | [[Category: Rrna methyltransferase]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 05:21, 10 October 2019
Crystal structure of 23S rRNA methyltransferase ErmE
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