6oms

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'''Unreleased structure'''
 
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The entry 6oms is ON HOLD until Paper Publication
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==Arabidopsis GH3.12 with Chorismate==
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<StructureSection load='6oms' size='340' side='right'caption='[[6oms]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6oms]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OMS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6OMS FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=ISJ:(3R,4R)-3-[(1-CARBOXYETHENYL)OXY]-4-HYDROXYCYCLOHEXA-1,5-DIENE-1-CARBOXYLIC+ACID'>ISJ</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6oms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6oms OCA], [http://pdbe.org/6oms PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6oms RCSB], [http://www.ebi.ac.uk/pdbsum/6oms PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6oms ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/GH312_ARATH GH312_ARATH]] Catalyzes the conjugation of specific amino acids (e.g. Glu and possibly His, Lys, and Met) to their preferred acyl substrates (e.g. 4-substituted benzoates), in a magnesium ion- and ATP-dependent manner. Can use 4-substituted benzoates such as 4-aminobenzoate (pABA), 4-fluorobenzoate and 4-hydroxybenzoate (4-HBA), and, to a lesser extent, benzoate, vanillate and trans-cinnamate, but not 2-substituted benzoates and salicylic acid (SA), as conjugating acyl substrates. Involved in both basal and induced resistance in a SA-dependent manner. Confers resistance to virulent and avirulent pathogens (at least bacteria and oomycetes), and promotes SA glucosides accumulation. Required for the establishment of hyper-sensitive response (HR) upon incompatible interaction and subsequent systemic acquired resistance (SAR).<ref>PMID:18266921</ref> <ref>PMID:10224270</ref> <ref>PMID:11846877</ref> <ref>PMID:16353557</ref> <ref>PMID:17918621</ref> <ref>PMID:17521413</ref> <ref>PMID:17468220</ref> <ref>PMID:19189963</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Holland, C K]]
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[[Category: Jez, J M]]
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[[Category: Westfall, C S]]
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[[Category: Zubieta, C]]
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[[Category: Acyl acid-amido synthetase]]
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[[Category: Ligase]]

Revision as of 05:21, 10 October 2019

Arabidopsis GH3.12 with Chorismate

PDB ID 6oms

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