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6ugf
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Katanin hexamer in the ring conformation with resolved protomer one in complex with substrate== | |
| - | + | <StructureSection load='6ugf' size='340' side='right'caption='[[6ugf]], [[Resolution|resolution]] 4.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ugf]] is a 7 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UGF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UGF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Microtubule-severing_ATPase Microtubule-severing ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.6.1.1 5.6.1.1] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ugf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ugf OCA], [http://pdbe.org/6ugf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ugf RCSB], [http://www.ebi.ac.uk/pdbsum/6ugf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ugf ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/KTNA1_CAEEL KTNA1_CAEEL]] Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays. Required specifically for meiotic spindle formation in the female germline; the presence of this protein is inimical to the formation of mitotic spindles (PubMed:8027178, PubMed:10809666, PubMed:12885567). In body wall muscles, regulates organization of myosin thick filaments (PubMed:22621901).[HAMAP-Rule:MF_03023]<ref>PMID:10809666</ref> <ref>PMID:12885567</ref> <ref>PMID:22621901</ref> <ref>PMID:8027178</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Microtubule-severing ATPase]] | ||
| + | [[Category: Roll-Mecak, A]] | ||
| + | [[Category: Zehr, E A]] | ||
| + | [[Category: Katanin]] | ||
| + | [[Category: Mei-1]] | ||
| + | [[Category: Microtubule cytoskeleton]] | ||
| + | [[Category: Microtubule-severing]] | ||
| + | [[Category: Motor protein]] | ||
Revision as of 05:29, 10 October 2019
Katanin hexamer in the ring conformation with resolved protomer one in complex with substrate
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