6jt2
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of human soluble guanylate cyclase in the NO activated state== | |
| - | + | <StructureSection load='6jt2' size='340' side='right'caption='[[6jt2]], [[Resolution|resolution]] 3.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6jt2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JT2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JT2 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=G2P:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>G2P</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | [[Category: | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GUCY1A1, GUC1A3, GUCSA3, GUCY1A3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), GUCY1B1, GUC1B3, GUCSB3, GUCY1B3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Guanylate_cyclase Guanylate cyclase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.2 4.6.1.2] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jt2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jt2 OCA], [http://pdbe.org/6jt2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jt2 RCSB], [http://www.ebi.ac.uk/pdbsum/6jt2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jt2 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/GCYA1_HUMAN GCYA1_HUMAN]] Moyamoya disease with early-onset achalasia. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Guanylate cyclase]] | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen, L]] | ||
| + | [[Category: Kang, Y]] | ||
| + | [[Category: Liu, R]] | ||
| + | [[Category: Wu, J X]] | ||
| + | [[Category: Signaling protein]] | ||
| + | [[Category: Soluble guanylate cyclase]] | ||
Revision as of 06:08, 10 October 2019
Structure of human soluble guanylate cyclase in the NO activated state
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