5ibe

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==Crystal structure Mycobacterium tuberculosis CYP121 in complex with inhibitor fragment 25a==
==Crystal structure Mycobacterium tuberculosis CYP121 in complex with inhibitor fragment 25a==
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<StructureSection load='5ibe' size='340' side='right' caption='[[5ibe]], [[Resolution|resolution]] 1.62&Aring;' scene=''>
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<StructureSection load='5ibe' size='340' side='right'caption='[[5ibe]], [[Resolution|resolution]] 1.62&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ibe]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IBE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IBE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ibe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IBE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IBE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=69M:4-[5-AMINO-4-(3-AMINO[1,1-BIPHENYL]-3-YL)-1H-PYRAZOL-3-YL]PHENOL'>69M</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=69M:4-[5-AMINO-4-(3-AMINO[1,1-BIPHENYL]-3-YL)-1H-PYRAZOL-3-YL]PHENOL'>69M</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cyp121, MT2336 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mycocyclosin_synthase Mycocyclosin synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.21.9 1.14.21.9] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mycocyclosin_synthase Mycocyclosin synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.21.9 1.14.21.9] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ibe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ibe OCA], [http://pdbe.org/5ibe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ibe RCSB], [http://www.ebi.ac.uk/pdbsum/5ibe PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ibe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ibe OCA], [http://pdbe.org/5ibe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ibe RCSB], [http://www.ebi.ac.uk/pdbsum/5ibe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ibe ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</div>
</div>
<div class="pdbe-citations 5ibe" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5ibe" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Mycocyclosin synthase]]
[[Category: Mycocyclosin synthase]]
[[Category: Levy, C]]
[[Category: Levy, C]]

Revision as of 06:22, 16 October 2019

Crystal structure Mycobacterium tuberculosis CYP121 in complex with inhibitor fragment 25a

PDB ID 5ibe

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