5j3s
From Proteopedia
(Difference between revisions)
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==Crystal structure of the catalytic domain of human tyrosyl DNA phosphodiesterase 2 in complex with a small molecule inhibitor== | ==Crystal structure of the catalytic domain of human tyrosyl DNA phosphodiesterase 2 in complex with a small molecule inhibitor== | ||
| - | <StructureSection load='5j3s' size='340' side='right' caption='[[5j3s]], [[Resolution|resolution]] 3.40Å' scene=''> | + | <StructureSection load='5j3s' size='340' side='right'caption='[[5j3s]], [[Resolution|resolution]] 3.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5j3s]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J3S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5J3S FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5j3s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J3S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5J3S FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6FQ:2,4-DIOXO-10-[3-(1H-TETRAZOL-5-YL)PHENYL]-2,3,4,10-TETRAHYDROPYRIMIDO[4,5-B]QUINOLINE-8-CARBONITRILE'>6FQ</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6FQ:2,4-DIOXO-10-[3-(1H-TETRAZOL-5-YL)PHENYL]-2,3,4,10-TETRAHYDROPYRIMIDO[4,5-B]QUINOLINE-8-CARBONITRILE'>6FQ</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TDP2, EAP2, TTRAP, AD-022 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5j3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j3s OCA], [http://pdbe.org/5j3s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j3s RCSB], [http://www.ebi.ac.uk/pdbsum/5j3s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5j3s ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5j3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j3s OCA], [http://pdbe.org/5j3s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j3s RCSB], [http://www.ebi.ac.uk/pdbsum/5j3s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5j3s ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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</div> | </div> | ||
<div class="pdbe-citations 5j3s" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5j3s" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Phosphodiesterase|Phosphodiesterase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Caldecott, K W]] | [[Category: Caldecott, K W]] | ||
[[Category: Hornyak, P]] | [[Category: Hornyak, P]] | ||
Revision as of 06:24, 16 October 2019
Crystal structure of the catalytic domain of human tyrosyl DNA phosphodiesterase 2 in complex with a small molecule inhibitor
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