This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1mh1
From Proteopedia
| Line 1: | Line 1: | ||
[[Image:1mh1.jpg|left|200px]] | [[Image:1mh1.jpg|left|200px]] | ||
| - | + | <!-- | |
| - | + | The line below this paragraph, containing "STRUCTURE_1mh1", creates the "Structure Box" on the page. | |
| - | + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | |
| - | + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | |
| - | + | or leave the SCENE parameter empty for the default display. | |
| - | + | --> | |
| - | + | {{STRUCTURE_1mh1| PDB=1mh1 | SCENE= }} | |
| - | | | + | |
| - | | | + | |
| - | }} | + | |
'''SMALL G-PROTEIN''' | '''SMALL G-PROTEIN''' | ||
| Line 32: | Line 29: | ||
[[Category: Stockley, R W.]] | [[Category: Stockley, R W.]] | ||
[[Category: Webb, M R.]] | [[Category: Webb, M R.]] | ||
| - | [[Category: | + | [[Category: Gtp-binding]] |
| - | [[Category: | + | [[Category: Gtpase]] |
| - | [[Category: | + | [[Category: Ras super family]] |
| - | [[Category: | + | [[Category: Rho family]] |
| - | [[Category: | + | [[Category: Small g-protein]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 30 13:34:28 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 10:34, 30 April 2008
SMALL G-PROTEIN
Contents |
Overview
The crystal structure of human rac1, a member of the rho family of small G-proteins, complexed with the non-hydrolysable GTP analogue, guanosine-5'-(beta gamma-imino)triphosphate (GMPPNP), has been determined by X-ray analysis at a resolution of 1.38 A. Comparison with the structure of H-ras indicates that rac1 has an extra alpha-helical domain that is characteristic of the rho G proteins, and may be involved in the signalling pathway of this family.
Disease
Known disease associated with this structure: Night blindness, congenital stationery, rhodopsin-related OMIM:[180380], Retinitis pigmentosa, autosomal recessive OMIM:[180380], Retinitis pigmentosa-4, autosomal dominant OMIM:[180380]
About this Structure
1MH1 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue., Hirshberg M, Stockley RW, Dodson G, Webb MR, Nat Struct Biol. 1997 Feb;4(2):147-52. PMID:9033596 Page seeded by OCA on Wed Apr 30 13:34:28 2008
