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5wt4
From Proteopedia
(Difference between revisions)
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==L-Cysteine-PLP intermediate of NifS from Helicobacter pylori== | ==L-Cysteine-PLP intermediate of NifS from Helicobacter pylori== | ||
| - | <StructureSection load='5wt4' size='340' side='right' caption='[[5wt4]], [[Resolution|resolution]] 2.92Å' scene=''> | + | <StructureSection load='5wt4' size='340' side='right'caption='[[5wt4]], [[Resolution|resolution]] 2.92Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5wt4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WT4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WT4 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5wt4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WT4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WT4 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C6P:N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-CYSTEINE'>C6P</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C6P:N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-CYSTEINE'>C6P</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5wt2|5wt2]], [[5wt5|5wt5]], [[5wt6|5wt6]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5wt2|5wt2]], [[5wt5|5wt5]], [[5wt6|5wt6]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">iscS, HP_0220 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=85962 Campylobacter pylori])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cysteine_desulfurase Cysteine desulfurase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.1.7 2.8.1.7] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cysteine_desulfurase Cysteine desulfurase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.1.7 2.8.1.7] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wt4 OCA], [http://pdbe.org/5wt4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wt4 RCSB], [http://www.ebi.ac.uk/pdbsum/5wt4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wt4 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wt4 OCA], [http://pdbe.org/5wt4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wt4 RCSB], [http://www.ebi.ac.uk/pdbsum/5wt4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wt4 ProSAT]</span></td></tr> | ||
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== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/ISCS_HELPY ISCS_HELPY]] Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | [[http://www.uniprot.org/uniprot/ISCS_HELPY ISCS_HELPY]] Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Cysteine desulfurase 3D structures|Cysteine desulfurase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Campylobacter pylori]] | ||
[[Category: Cysteine desulfurase]] | [[Category: Cysteine desulfurase]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Fujishiro, T]] | [[Category: Fujishiro, T]] | ||
[[Category: Nakamura, R]] | [[Category: Nakamura, R]] | ||
Revision as of 06:59, 16 October 2019
L-Cysteine-PLP intermediate of NifS from Helicobacter pylori
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