This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.

6et5

From Proteopedia

(Difference between revisions)

Jump to: navigation, search

Revision as of 07:52, 23 October 2019

Reaction centre light harvesting complex 1 from Blc. virids

Structural highlights

6et5 is a 54 chain structure with sequence from Blastochloris viridis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	, , , , , , , , ,
NonStd Res:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[LHB_BLAVI] Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers. [RCEH_BLAVI] The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis. [CYCR_BLAVI] The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor.^[1] [RCEM_BLAVI] The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis. [LHG_BLAVI] One of the components of the bacteriochlorophyll-protein complex in the chromatophore membrane. [RCEL_BLAVI] The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis. [LHA_BLAVI] Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.

Publication Abstract from PubMed

The light-harvesting 1-reaction centre (LH1-RC) complex is a key functional component of bacterial photosynthesis. Here we present a 2.9 A resolution cryo-electron microscopy structure of the bacteriochlorophyll b-based LH1-RC complex from Blastochloris viridis that reveals the structural basis for absorption of infrared light and the molecular mechanism of quinone migration across the LH1 complex. The triple-ring LH1 complex comprises a circular array of 17 beta-polypeptides sandwiched between 17 alpha- and 16 gamma-polypeptides. Tight packing of the gamma-apoproteins between beta-polypeptides collectively interlocks and stabilizes the LH1 structure; this, together with the short Mg-Mg distances of bacteriochlorophyll b pairs, contributes to the large redshift of bacteriochlorophyll b absorption. The 'missing' 17th gamma-polypeptide creates a pore in the LH1 ring, and an adjacent binding pocket provides a folding template for a quinone, Q P, which adopts a compact, export-ready conformation before passage through the pore and eventual diffusion to the cytochrome bc 1 complex.

Cryo-EM structure of the Blastochloris viridis LH1-RC complex at 2.9 A.,Qian P, Siebert CA, Wang P, Canniffe DP, Hunter CN Nature. 2018 Apr;556(7700):203-208. doi: 10.1038/s41586-018-0014-5. Epub 2018 Apr, 4. PMID:29618818^[2]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Chen IP, Mathis P, Koepke J, Michel H. Uphill electron transfer in the tetraheme cytochrome subunit of the Rhodopseudomonas viridis photosynthetic reaction center: evidence from site-directed mutagenesis. Biochemistry. 2000 Apr 4;39(13):3592-602. PMID:10736158
↑ Qian P, Siebert CA, Wang P, Canniffe DP, Hunter CN. Cryo-EM structure of the Blastochloris viridis LH1-RC complex at 2.9 A. Nature. 2018 Apr;556(7700):203-208. doi: 10.1038/s41586-018-0014-5. Epub 2018 Apr, 4. PMID:29618818 doi:http://dx.doi.org/10.1038/s41586-018-0014-5

1 Structural highlights
2 Function
3 Publication Abstract from PubMed
4 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6et5"

@@ Line 1: / Line 1: @@
 ==Reaction centre light harvesting complex 1 from Blc. virids==
-<StructureSection load='6et5' size='340' side='right' caption='[[6et5]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
+<StructureSection load='6et5' size='340' side='right'caption='[[6et5]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
 == Structural highlights ==
 <table><tr><td colspan='2'>[[6et5]] is a 54 chain structure with sequence from [http://en.wikipedia.org/wiki/Blastochloris_viridis Blastochloris viridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ET5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ET5 FirstGlance]. <br>
@@ Line 24: / Line 24: @@
 </StructureSection>
 [[Category: Blastochloris viridis]]
+[[Category: Large Structures]]
 [[Category: Canniffe, D P]]
 [[Category: Hunter, C N]]

6et5

From Proteopedia

Revision as of 07:52, 23 October 2019

Reaction centre light harvesting complex 1 from Blc. virids

Structural highlights

Function

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

Personal tools

Navigation

Search

Toolbox