Sandbox Reserved 1576
From Proteopedia
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==Overview== | ==Overview== | ||
<StructureSection load='1y26' size='340' side='right' caption='A-riboswitch-adenenine complex 3D model' scene=''> | <StructureSection load='1y26' size='340' side='right' caption='A-riboswitch-adenenine complex 3D model' scene=''> | ||
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| - | + | Riboswitches are metabolite-sensing-mRNAs that interact with small ligands and direct expression of the genes involved in their metabolism. | |
== Structure == | == Structure == | ||
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| + | The adenine bound A-riboswitch complex adopts a tuning fork-like | ||
| + | compact fold (schematic in Figure 4A; structures in Figures 4B and 4C), where stem P1 forms the handle of the tuning fork, and stems P2 and P3, which form the prongs, are aligned parallel to each other and anchored at the tips through extensive interaction between their hairpin loops L2 and L3. The central internal bubble zippers up through stacked base triple alignments between the three junction-connecting segments, J1-2, J2-3, and J3-1, and two junctional base pairs of stem P1, thereby generating an adenine-sensing pocket within the resulting core segment of the RNA scaffold. | ||
== Relevance == | == Relevance == | ||
Revision as of 17:33, 23 October 2019
| This Sandbox is Reserved from September 14, 2021, through May 31, 2022, for use in the class Introduction to Biochemistry taught by User:John Means at the University of Rio Grande, Rio Grande, OH, USA. This reservation includes 5 reserved sandboxes (Sandbox Reserved 1590 through Sandbox Reserved 1594). |
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More help: Help:Editing. For an example of a student Proteopedia page, please see Photosystem II, Tetanospasmin, or Guanine riboswitch. |
Overview
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