6t17
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of the wild-type flagellar filament of the Firmicute Kurthia== | |
| + | <StructureSection load='6t17' size='340' side='right'caption='[[6t17]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6t17]] is a 44 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6T17 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6T17 FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6t17 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6t17 OCA], [http://pdbe.org/6t17 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6t17 RCSB], [http://www.ebi.ac.uk/pdbsum/6t17 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6t17 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/A0A0X9VHV9_9BACL A0A0X9VHV9_9BACL]] Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.[RuleBase:RU362073] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Bacteria swim and swarm by rotating the micrometers long, helical filaments of their flagella. They change direction by reversing their flagellar rotation, which switches the handedness of the filament's supercoil. So far, all studied functional filaments are composed of a mixture of L- and R-state flagellin monomers. Here we show in a study of the wild type Firmicute Kurthia sp., that curved, functional filaments can adopt a conformation in vivo that is closely related to a uniform, all-L-state. This sheds additional light on transitions of the flagellar supercoil and uniquely reveals the atomic structure of a wild-type flagellar filament in vivo, including six residues showing clearly densities of O-linked glycosylation. | ||
| - | + | The wild-type flagellar filament of the Firmicute Kurthia at 2.8 A resolution in vivo.,Blum TB, Filippidou S, Fatton M, Junier P, Abrahams JP Sci Rep. 2019 Oct 18;9(1):14948. doi: 10.1038/s41598-019-51440-1. PMID:31628388<ref>PMID:31628388</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| - | [[Category: Abrahams, J | + | <div class="pdbe-citations 6t17" style="background-color:#fffaf0;"></div> |
| - | [[Category: Blum, T | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Abrahams, J P]] | ||
| + | [[Category: Blum, T B]] | ||
| + | [[Category: Gram-positive bacteria flagella]] | ||
| + | [[Category: Helical]] | ||
| + | [[Category: Protein fibril]] | ||
| + | [[Category: Wild-type]] | ||
Revision as of 09:11, 30 October 2019
Cryo-EM structure of the wild-type flagellar filament of the Firmicute Kurthia
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