5fp3

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==Cell penetrant inhibitors of the JMJD2 (KDM4) and JARID1 (KDM5) families of histone lysine demethylases==
==Cell penetrant inhibitors of the JMJD2 (KDM4) and JARID1 (KDM5) families of histone lysine demethylases==
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<StructureSection load='5fp3' size='340' side='right' caption='[[5fp3]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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<StructureSection load='5fp3' size='340' side='right'caption='[[5fp3]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5fp3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FP3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FP3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5fp3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FP3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FP3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3JI:3-(4-PHENYLBUTANAMIDO)PYRIDINE-4-CARBOXYLIC+ACID'>3JI</scene>, <scene name='pdbligand=BCN:BICINE'>BCN</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCN:BICINE'>BCN</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=YC8:3-(4-PHENYLBUTANOYLAMINO)PYRIDINE-4-CARBOXYLIC+ACID'>YC8</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5fp4|5fp4]], [[5fp7|5fp7]], [[5fp8|5fp8]], [[5fp9|5fp9]], [[5fpa|5fpa]], [[5fpb|5fpb]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5fp4|5fp4]], [[5fp7|5fp7]], [[5fp8|5fp8]], [[5fp9|5fp9]], [[5fpa|5fpa]], [[5fpb|5fpb]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fp3 OCA], [http://pdbe.org/5fp3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fp3 RCSB], [http://www.ebi.ac.uk/pdbsum/5fp3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fp3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fp3 OCA], [http://pdbe.org/5fp3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fp3 RCSB], [http://www.ebi.ac.uk/pdbsum/5fp3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fp3 ProSAT]</span></td></tr>
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==See Also==
==See Also==
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*[[Jumonji domain-containing protein|Jumonji domain-containing protein]]
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*[[Jumonji domain-containing protein 3D structures|Jumonji domain-containing protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Chung, C]]
[[Category: Chung, C]]
[[Category: Inhibitor]]
[[Category: Inhibitor]]

Revision as of 09:22, 30 October 2019

Cell penetrant inhibitors of the JMJD2 (KDM4) and JARID1 (KDM5) families of histone lysine demethylases

PDB ID 5fp3

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