6qb6
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Mcl1 in complex with a Fab== | |
| - | + | <StructureSection load='6qb6' size='340' side='right'caption='[[6qb6]], [[Resolution|resolution]] 2.24Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6qb6]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QB6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QB6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6qb3|6qb3]], [[6qb4|6qb4]], [[6fs0|6fs0]]</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qb6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qb6 OCA], [http://pdbe.org/6qb6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qb6 RCSB], [http://www.ebi.ac.uk/pdbsum/6qb6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qb6 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MCL1_HUMAN MCL1_HUMAN]] Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.<ref>PMID:10766760</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Hargreaves, D]] | [[Category: Hargreaves, D]] | ||
| + | [[Category: Apoptosis]] | ||
| + | [[Category: Azd5991]] | ||
| + | [[Category: Fab]] | ||
| + | [[Category: Mcl1]] | ||
Revision as of 06:47, 6 November 2019
Mcl1 in complex with a Fab
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Categories: Large Structures | Hargreaves, D | Apoptosis | Azd5991 | Fab | Mcl1
