6qfc
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of an anti-Mcl1 scFv== | |
| + | <StructureSection load='6qfc' size='340' side='right'caption='[[6qfc]], [[Resolution|resolution]] 1.96Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6qfc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QFC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QFC FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6fs0|6fs0]], [[6qb3|6qb3]], [[6qb4|6qb4]]</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qfc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qfc OCA], [http://pdbe.org/6qfc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qfc RCSB], [http://www.ebi.ac.uk/pdbsum/6qfc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qfc ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MCL1_HUMAN MCL1_HUMAN]] Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.<ref>PMID:10766760</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Kallikrein 3D structures|Kallikrein 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Luptak, J]] | [[Category: Luptak, J]] | ||
| + | [[Category: Apoptosis]] | ||
| + | [[Category: Mcl1]] | ||
| + | [[Category: Scfv]] | ||
Revision as of 06:48, 6 November 2019
Structure of an anti-Mcl1 scFv
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Categories: Large Structures | Luptak, J | Apoptosis | Mcl1 | Scfv
