6tzm

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'''Unreleased structure'''
 
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The entry 6tzm is ON HOLD until Paper Publication
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==Crystal Structure of Fungal RNA Kinase==
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<StructureSection load='6tzm' size='340' side='right'caption='[[6tzm]], [[Resolution|resolution]] 1.71&Aring;' scene=''>
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Authors: Shuman, S., Goldgur, Y., Banerjee, A.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6tzm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TZM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TZM FirstGlance]. <br>
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Description: Crystal Structure of Fungal RNA Kinase
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5u32|5u32]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA_ligase_(ATP) RNA ligase (ATP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.3 6.5.1.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tzm OCA], [http://pdbe.org/6tzm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tzm RCSB], [http://www.ebi.ac.uk/pdbsum/6tzm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tzm ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/TRNL_CANAL TRNL_CANAL]] One of the two proteins required for the splicing of precursor tRNA molecules containing introns. The ligation activity requires three enzymatic activities: phosphorylation of the 5' terminus of the 3' half-tRNA in the presence of ATP, opening of the 2'3'-cyclic phosphodiester bond of the 5' half-tRNA leaving a 2'-phosphomonoester and ligation of the two tRNA halves in an ATP-dependent reaction.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Banerjee, A]]
[[Category: Goldgur, Y]]
[[Category: Goldgur, Y]]
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[[Category: Banerjee, A]]
 
[[Category: Shuman, S]]
[[Category: Shuman, S]]
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[[Category: Polynucleotide kinase]]
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[[Category: Rna ligase]]
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[[Category: Rna repair]]
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[[Category: Transferase]]

Revision as of 06:54, 6 November 2019

Crystal Structure of Fungal RNA Kinase

PDB ID 6tzm

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