Neurexin
From Proteopedia
(Difference between revisions)
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*Neurexin | *Neurexin | ||
| + | **[[5z8y]] – hNRXN-1b + LRRTM2 – human<br /> | ||
**[[3mw2]] – mNRXN-1α LNS domain+splice insert 4 – mouse<br /> | **[[3mw2]] – mNRXN-1α LNS domain+splice insert 4 – mouse<br /> | ||
| - | **[[3bod]], [[3bop]] - mNRXN- | + | **[[3bod]], [[3bop]] - mβNRXN-1 residues 1132-1246 + mb-NRXN-2 residues 1277-1334<br /> |
| + | **[[3mw4]] - mβNRXN-3 residues 854-1027<br /> | ||
| + | **[[6pnp]], [[6pnq]] - mNRXN-1 LNS2 domain + neurexophilin-1<br /> | ||
**[[3mw3]], [[2r1b]] - rNRXN-1α LNS domain+splice insert 4 – rat<br /> | **[[3mw3]], [[2r1b]] - rNRXN-1α LNS domain+splice insert 4 – rat<br /> | ||
**[[2r16]] - rNRXN-1α LNS domain+Ca<br /> | **[[2r16]] - rNRXN-1α LNS domain+Ca<br /> | ||
**[[1c4r]] - rNRXN-1α LNS domain<br /> | **[[1c4r]] - rNRXN-1α LNS domain<br /> | ||
| - | **[[ | + | **[[2r1d]] - rNRXN-1β LNS/LG domain<br /> |
**[[2h0b]] - bNRXN-1α LNS2 domain – bovine<br /> | **[[2h0b]] - bNRXN-1α LNS2 domain – bovine<br /> | ||
| + | **[[6cw1]] - bNRXN-1 LNS2-LNS3 domains<br /> | ||
**[[3asi]] - bNRXN-1α LNS5-EGF3-LNS6 domains<br /> | **[[3asi]] - bNRXN-1α LNS5-EGF3-LNS6 domains<br /> | ||
**[[3poy]] - bNRXN-1α LNS2-LNS6 domains (mutant)<br /> | **[[3poy]] - bNRXN-1α LNS2-LNS6 domains (mutant)<br /> | ||
**[[3qcw]], [[3r05]] - bNRXN-1α LNS1-LNS6 domains (mutant)<br /> | **[[3qcw]], [[3r05]] - bNRXN-1α LNS1-LNS6 domains (mutant)<br /> | ||
| - | **[[2r1d]] - rNRXN-1β LNS/LG domain | ||
*NRXN+Neuroligin | *NRXN+Neuroligin | ||
Current revision
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3D Structures of Neurexin
07-November-2019
References
- ↑ Dean C, Scholl FG, Choih J, DeMaria S, Berger J, Isacoff E, Scheiffele P. Neurexin mediates the assembly of presynaptic terminals. Nat Neurosci. 2003 Jul;6(7):708-16. PMID:12796785 doi:http://dx.doi.org/10.1038/nn1074
- ↑ Kim HG, Kishikawa S, Higgins AW, Seong IS, Donovan DJ, Shen Y, Lally E, Weiss LA, Najm J, Kutsche K, Descartes M, Holt L, Braddock S, Troxell R, Kaplan L, Volkmar F, Klin A, Tsatsanis K, Harris DJ, Noens I, Pauls DL, Daly MJ, MacDonald ME, Morton CC, Quade BJ, Gusella JF. Disruption of neurexin 1 associated with autism spectrum disorder. Am J Hum Genet. 2008 Jan;82(1):199-207. doi: 10.1016/j.ajhg.2007.09.011. PMID:18179900 doi:http://dx.doi.org/10.1016/j.ajhg.2007.09.011
- ↑ Leone P, Comoletti D, Ferracci G, Conrod S, Garcia SU, Taylor P, Bourne Y, Marchot P. Structural insights into the exquisite selectivity of neurexin/neuroligin synaptic interactions. EMBO J. 2010 Jul 21;29(14):2461-71. Epub 2010 Jun 11. PMID:20543817 doi:10.1038/emboj.2010.123
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Michal Harel, Alexander Berchansky, David Canner, Joel L. Sussman, Jaime Prilusky
