Nucleoporin

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:08, 11 November 2019) (edit) (undo)
 
Line 13: Line 13:
</StructureSection>
</StructureSection>
-
== 3D Structures of Nucleoporin ==
 
- 
-
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
-
{{#tree:id=OrganizedByTopic|openlevels=0|
 
- 
-
*NUP2
 
-
**[[3n7c]] – NUP2 RANBD – ''Ashbya gossypii''<br />
 
-
**[[2c1t]] – yNUP2 NTD +importrin alpha subunit - yeast<br />
 
-
*NUP35
 
-
**[[1wwh]] – mNUP35 MPPN domain - mouse<br />
 
-
*NUP37
 
-
**[[4fhl]] – fyNUP37 – fission yeast<br />
 
-
**[[4fhm]], [[4fhn]], [[4gq2]] - fyNUP37 + NUP120<br />
 
-
*NUP43
 
-
**[[4i79]] – hNUP43 + polypeptide - human<br />
 
-
*NUP50
 
-
**[[2ec1]] – hNUP50 RANBD <br />
 
-
**[[3tj3]] - hNUP50 NTD+importin<br />
 
-
**[[2c1m]] – mNUP50 NTD +importin <br />
 
-
*NUP53
 
-
**[[3p3d]] - NUP53 RRM domain - ''Pischia guillermondii''<br />
 
-
**[[4lir]] – hNUP53 residues 151-266<br />
 
-
**[[5uaz]] – yNUP53 <br />
 
-
**[[5hb8]], [[5hb7]] – CtNUP53 - ''Chaetomium thermophilum''<br />
 
-
**[[5hb3]] – CtNUP53 + NUP NIC96 <br />
 
-
*NUP54
 
-
**[[4jo7]], [[4jo9]] – hNUP54 + hNUP58/45 <br />
 
-
**[[3t97]] – rNUP54 + NUP62 - rat<br />
 
-
**[[4j3h]] – rNUP54 (mutant)<br />
 
-
**[[3t98]] – rNUP54 + rNUP58/45 <br />
 
-
**[[5c3l]] – fNUP54 coiled coil + NUP58 coiled coil + NUP62 coiled coil + nanobody - frog<br />
 
-
**[[5c2u]] – fNUP54 ferredoxin-like domain + nanobody <br />
 
-
*NUP57
 
-
**[[5cwt]] – CtNUP57 residues 265-317<br />
 
-
**[[5cws]] – CtNUP57 residues 74-319 + NUP49 + NIC96 + antibody<br />
 
-
*NUP58
 
-
**[[4jq5]] – hNUP58/45 <br />
 
-
**[[2osz]] – rNUP58/45 <br />
 
-
*NUP62
 
-
**[[5h1x]] – rNUP62 coiled-coil domain<br />
 
-
*NUP82
 
-
**[[3pbp]] – yNUP82 NTD + NUP116 CTD + NUP159 CTD<br />
 
-
**[[3tkn]] - yNUP82 NTD + NUP98 + NUP159 CTD<br />
 
-
**[[5cww]] – CtNUP82 + CtNUP145 CTD peptide + Ct159 CTD peptide<br />
 
-
*NUP84
 
-
**[[3jro]], [[3iko]] – yNUP84+NUP145+protein Sec13<br />
 
-
**[[4xmm]] - yNUP84+NUP85+NUP120+NUP145+protein Seh1 + antibody<br />
 
-
**[[4xmn]] - yNUP84+NUP85+NUP120+NUP145 + antibody<br />
 
-
*NUP85
 
-
**[[3f3f]], [[3f3g]], [[3f3p]], [[3ewe]] – yNUP85+Seh1<br />
 
-
*NUP98
 
-
**[[3mmy]] – hNUP98 fragment+mRNA export factor <br />
 
-
**[[2q5x]], [[2q5y]] – hNUP98 CTD<br />
 
-
**[[1ko6]] – hNUP98 CTD<br />
 
-
*NUP100
 
-
**[[3nf5]] – NUP100 CTD – ''Candida glabrata''<br />
 
-
*NUP107
 
-
**[[3i4r]], [[3cqc]], [[3cqg]] – hNUP107+NUP133<br />
 
-
*NUP116
 
-
**[[2aiv]] – yNUP116 CTD - NMR<br />
 
-
*NUP120
 
-
**[[3f7f]], [[3h7n]], [[3hxr]] – yNUP120<br />
 
-
*NUP133
 
-
**[[1xks]], [[4q9t]] – hNUP133 NTD<br />
 
-
**[[3kfo]] – yNUP133 CTD <br />
 
-
*NUP145
 
-
**[[3bg0]], [[3bg1]] – hNUP145+Sec13-related protein<br />
 
-
**[[3kep]], [[3kes]] – yNUP145 autoproteolytic domain<br />
 
-
**[[3jrp]] - yNUP145+protein Sec13<br />
 
-
**[[5hb5]] – CtNUP145 <br />
 
-
**[[5hb6]] – CtNUP145 (mutant)<br />
 
-
*NUP152
 
-
**[[5tvz]] – yNUP152 Ig-like repeats - NMR<br />
 
-
*NUP153
 
-
**[[3gj3]], [[3gj4]], [[3gj5]], [[3gj6]], [[3gj7]], [[3gj8]], [[3ch5]] – hNUP153+RAN<br />
 
-
**[[2ebq]], [[2ebr]], [[2ebv]], [[2gqe]] - hNUP153 RANBD – NMR<br />
 
-
**[[2k0c]] – rNUP153 RANBD – NMR<br />
 
-
*NUP157
 
-
**[[4mhc]] – hNUP157 NTD<br />
 
-
*NUP159
 
-
**[[1xip]] – yNUP159 NTD<br />
 
-
**[[3rrm]] – yNUP159 residues 2-387 + NUP Gle1 + IP6 + ADP<br />
 
-
*NUP170
 
-
**[[3i5p]], [[3i5q]] – yNUP170<br />
 
-
**[[5hb1]] – CtNUP170 <br />
 
-
**[[5haz]] – CtNUP170 CTD<br />
 
-
**[[5hay]] – CtNUP170 CTD (mutant)<br />
 
-
**[[5hb0]] – CtNUP170 (mutant) + CtNUP145 peptide<br />
 
-
**[[5hax]] – CtNUP170 NTD + CtNUP53 peptide<br />
 
-
*NUP188
 
-
**[[5cwu]] – CtNUP192 tail domain<br />
 
-
*NUP192
 
-
**[[4ifq]] – yNUP192<br />
 
-
**[[5hb4]] – CtNUP192 <br />
 
-
**[[5cwv]] – CtNUP192 tail domain<br />
 
-
*NUP214
 
-
**[[3fmo]], [[3fmp]], [[3fhc]] – hNUP214+dead-box helicase<br />
 
-
**[[2oit]] – hNUP214 NTD<br />
 
-
*NUP358
 
-
**[[1z5s]] – hNUP358 IR1 domain+ubiquitin-conjugating enzyme+SMT3C+RAN CTD<br />
 
-
**[[1xke]] - hNUP358 RANBD - NMR<br />
 
-
*NUP1P
 
-
**[[5owu]] – NUP1P+Kap95 complex<br />
 
-
*NUP2P
 
-
**[[1un0]] – yNUP2P NTD+importrin α subunit<br />
 
-
*NUP-NSP1
 
-
**[[1o6o]] – yNUP-NSP1 residues 497-608+importrin β subunit<br />
 
-
*NUP-CDC31
 
-
**[[2doq]], [[2gv5]] – yNUP-CDC31+SFI1P<br />
 
-
**[[3fwb]], [[3fwc]] - yNUP-CDC31+SAC3<br />
 
- 
-
*NUP Gle1
 
-
**[[3peu]], [[3pev]], [[3rrn]]– yNUP-Gle1 + ATP-dependent RNA helicase Dbp5 (mutant) +IP6<br />
 
-
**[[6b4e]] – yNUP-Gle1 + NUP42 <br />
 
-
**[[6b4g]], [[6b4h]] – CtNUP-Gle1 + NUP Amo1 <br />
 
- 
-
*Nuclear pore complex
 
- 
-
**[[5ijo]], [[5ijn]] – hNUP93 + NUP155 + NUP205 + NUP54 + NUP58 + NUP62 + NUP188 – Cryo EM<br />
 
-
**[[5a9q]] – hNUP96 + NUP133 + NUP160 + NUP43 + NUP37 + NUP85 + NUP155 + NUP107 + Sec13 + Seh1 – Cryo EM<br />
 
- 
-
**[[2rfo]], [[2qx5]] – yNic96<br />
 
-
**[[5hb2]] – CtNic96 <br />
 
-
**[[1gyb]] – NUP+yNTF2<br />
 
-
}}
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Yeast nucleoporin NUP159 N-terminal domain (PDB entry 1xip)

Drag the structure with the mouse to rotate

References

  1. Doye V, Hurt E. From nucleoporins to nuclear pore complexes. Curr Opin Cell Biol. 1997 Jun;9(3):401-11. PMID:9159086
  2. Belanger KD, Kenna MA, Wei S, Davis LI. Genetic and physical interactions between Srp1p and nuclear pore complex proteins Nup1p and Nup2p. J Cell Biol. 1994 Aug;126(3):619-30. PMID:8045927
  3. Solsbacher J, Maurer P, Vogel F, Schlenstedt G. Nup2p, a yeast nucleoporin, functions in bidirectional transport of importin alpha. Mol Cell Biol. 2000 Nov;20(22):8468-79. PMID:11046143
  4. Cronshaw JM, Matunis MJ. The nuclear pore complex: disease associations and functional correlations. Trends Endocrinol Metab. 2004 Jan-Feb;15(1):34-9. PMID:14693424

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Alexander Berchansky, Jaime Prilusky

Personal tools