Pantothenate kinase
From Proteopedia
(Difference between revisions)
| Line 15: | Line 15: | ||
<scene name='52/525168/Cv/5'>Pantothenate binds in a buried pocket at the PanK dimer interface</scene><ref>PMID:16905099</ref>. | <scene name='52/525168/Cv/5'>Pantothenate binds in a buried pocket at the PanK dimer interface</scene><ref>PMID:16905099</ref>. | ||
*<scene name='52/525168/Cv/6'>Buried pocket at the PanK dimer interface</scene>. | *<scene name='52/525168/Cv/6'>Buried pocket at the PanK dimer interface</scene>. | ||
| + | |||
| + | ==3D structures of pantothenate kinase== | ||
| + | [[Pantothenate kinase 3D structures]] | ||
| + | |||
</StructureSection> | </StructureSection> | ||
==3D structures of pantothenate kinase== | ==3D structures of pantothenate kinase== | ||
| Line 58: | Line 62: | ||
**[[2ews]] - SaPanK + ANP – ''Staphylococcus aureus''<br /> | **[[2ews]] - SaPanK + ANP – ''Staphylococcus aureus''<br /> | ||
| - | **[[4nb4]], [[4m7x]], [[4m7y]], [[5elz]], [[5jic]] - SaPanK + ADP + pantothenate derivative<br /> | + | **[[4nb4]], [[4m7x]], [[4m7y]], [[5elz]], [[5jic]], [[6avp]], [[6awi]], [[6awj]], [[6ebv]] - SaPanK + ADP + pantothenate derivative<br /> |
| + | **[[6awh]] - SaPanK + ATP + pantothenate derivative<br /> | ||
| + | **[[6awg]] - SaPanK + ADP + ATP + pantothenate derivative<br /> | ||
*'''PanK III''' | *'''PanK III''' | ||
| Line 91: | Line 97: | ||
**[[5kpz]] - hPanK 3 + ADP + PAU <br /> | **[[5kpz]] - hPanK 3 + ADP + PAU <br /> | ||
**[[5kqd]] - hPanK 3 + palmitoyl-CoA <br /> | **[[5kqd]] - hPanK 3 + palmitoyl-CoA <br /> | ||
| + | **[[6b3v]] - hPanK 3 + ANP + drug <br /> | ||
}} | }} | ||
Revision as of 09:08, 13 November 2019
| |||||||||||
3D structures of pantothenate kinase
Updated on 13-November-2019
References
- ↑ . PanK is regulated by feedback inhibition by CoA and its thioesters.PMID:9890959
- ↑ Pellecchia MT, Valente EM, Cif L, Salvi S, Albanese A, Scarano V, Bonuccelli U, Bentivoglio AR, D'Amico A, Marelli C, Di Giorgio A, Coubes P, Barone P, Dallapiccola B. The diverse phenotype and genotype of pantothenate kinase-associated neurodegeneration. Neurology. 2005 May 24;64(10):1810-2. PMID:15911822 doi:http://dx.doi.org/10.1212/01.WNL.0000161843.52641.EC
- ↑ Hong BS, Yun MK, Zhang YM, Chohnan S, Rock CO, White SW, Jackowski S, Park HW, Leonardi R. Prokaryotic type II and type III pantothenate kinases: The same monomer fold creates dimers with distinct catalytic properties. Structure. 2006 Aug;14(8):1251-61. PMID:16905099 doi:10.1016/j.str.2006.06.008
