6kk1
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of thermal-stabilised(M8) human GLP-1 receptor transmembrane domain== | |
| - | + | <StructureSection load='6kk1' size='340' side='right'caption='[[6kk1]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6kk1]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KK1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6KK1 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=97Y:N-{4-[(R)-(3,3-DIMETHYLCYCLOBUTYL)({6-[4-(TRIFLUOROMETHYL)-1H-IMIDAZOL-1-YL]PYRIDIN-3-YL}AMINO)METHYL]BENZENE-1-CARBONYL}-BETA-ALANINE'>97Y</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5vew|5vew]]</td></tr> |
| - | [[Category: Song, G | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6kk1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kk1 OCA], [http://pdbe.org/6kk1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6kk1 RCSB], [http://www.ebi.ac.uk/pdbsum/6kk1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6kk1 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GLP1R_HUMAN GLP1R_HUMAN]] This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Song, G J]] | ||
| + | [[Category: Allosteric modulator]] | ||
| + | [[Category: Diabetes]] | ||
| + | [[Category: Gpcr]] | ||
| + | [[Category: Seven-transmembrane]] | ||
| + | [[Category: Signaling protein]] | ||
Revision as of 11:00, 13 November 2019
Structure of thermal-stabilised(M8) human GLP-1 receptor transmembrane domain
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