6o6w
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Solution structure of human myeloid-derived growth factor== | |
| - | + | <StructureSection load='6o6w' size='340' side='right'caption='[[6o6w]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6o6w]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6O6W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6O6W FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6o6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o6w OCA], [http://pdbe.org/6o6w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6o6w RCSB], [http://www.ebi.ac.uk/pdbsum/6o6w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6o6w ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MYDGF_HUMAN MYDGF_HUMAN]] Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway (By similarity). Involved in endothelial cell proliferation and angiogenesis (PubMed:25581518).[UniProtKB:Q9CPT4]<ref>PMID:25581518</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bortnov, V]] | ||
| + | [[Category: Lee, W]] | ||
| + | [[Category: Markley, J L]] | ||
| + | [[Category: Mosher, D F]] | ||
| + | [[Category: Tonelli, M]] | ||
| + | [[Category: Endoplasmic reticulum]] | ||
| + | [[Category: Unknown function]] | ||
| + | [[Category: Upf0556]] | ||
Revision as of 11:05, 13 November 2019
Solution structure of human myeloid-derived growth factor
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