6ps5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 6ps5 is ON HOLD until Paper Publication
+
==XFEL beta2 AR structure by ligand exchange from Timolol to Propranolol.==
-
 
+
<StructureSection load='6ps5' size='340' side='right'caption='[[6ps5]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-
Authors:
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[6ps5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PS5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PS5 FirstGlance]. <br>
-
Description:
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=SNP:1-(ISOPROPYLAMINO)-3-(1-NAPHTHYLOXY)-2-PROPANOL'>SNP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ps5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ps5 OCA], [http://pdbe.org/6ps5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ps5 RCSB], [http://www.ebi.ac.uk/pdbsum/6ps5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ps5 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/ADRB2_HUMAN ADRB2_HUMAN]] Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Batyuk, A]]
 +
[[Category: Cherezov, C]]
 +
[[Category: Gati, C]]
 +
[[Category: Han, G W]]
 +
[[Category: Ishchenko, A]]
 +
[[Category: Iwata, S]]
 +
[[Category: Joti, Y]]
 +
[[Category: Li, C]]
 +
[[Category: Liu, W]]
 +
[[Category: Moraes, I]]
 +
[[Category: Nakane, T]]
 +
[[Category: Nango, E]]
 +
[[Category: Shiriaeva, A]]
 +
[[Category: Stauch, B]]
 +
[[Category: Tanaka, R]]
 +
[[Category: Tono, K]]
 +
[[Category: Weierstall, U]]
 +
[[Category: Zatsepin, N A]]
 +
[[Category: B2ar]]
 +
[[Category: Beta2ar]]
 +
[[Category: Complex-lcp method]]
 +
[[Category: Drug design]]
 +
[[Category: Gpcr]]
 +
[[Category: Lcp-sfx]]
 +
[[Category: Ligand exchange]]
 +
[[Category: Membrane protein]]
 +
[[Category: Propranolol]]
 +
[[Category: Sbdd]]
 +
[[Category: Timolol]]
 +
[[Category: Xfel]]

Revision as of 11:08, 13 November 2019

XFEL beta2 AR structure by ligand exchange from Timolol to Propranolol.

PDB ID 6ps5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6ps5"
Personal tools