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6ps7
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==XFEL A2aR structure by ligand exchange from LUF5843 to ZM241385.== | |
| - | + | <StructureSection load='6ps7' size='340' side='right'caption='[[6ps7]], [[Resolution|resolution]] 1.85Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ps7]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PS7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PS7 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLB:(2S)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLB</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=ZMA:4-{2-[(7-AMINO-2-FURAN-2-YL[1,2,4]TRIAZOLO[1,5-A][1,3,5]TRIAZIN-5-YL)AMINO]ETHYL}PHENOL'>ZMA</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ps7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ps7 OCA], [http://pdbe.org/6ps7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ps7 RCSB], [http://www.ebi.ac.uk/pdbsum/6ps7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ps7 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN]] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Batyuk, A]] | ||
| + | [[Category: Cherezov, C]] | ||
| + | [[Category: Gati, C]] | ||
| + | [[Category: Han, G W]] | ||
| + | [[Category: Ishchenko, A]] | ||
| + | [[Category: Iwata, S]] | ||
| + | [[Category: Joti, Y]] | ||
| + | [[Category: Li, C]] | ||
| + | [[Category: Liu, W]] | ||
| + | [[Category: Moraes, I]] | ||
| + | [[Category: Nakane, T]] | ||
| + | [[Category: Nango, E]] | ||
| + | [[Category: Shiriaeva, A]] | ||
| + | [[Category: Stauch, B]] | ||
| + | [[Category: Tanaka, R]] | ||
| + | [[Category: Tono, K]] | ||
| + | [[Category: Weierstall, U]] | ||
| + | [[Category: Zatsepin, N A]] | ||
| + | [[Category: A2aar]] | ||
| + | [[Category: Complex-lcp method]] | ||
| + | [[Category: Drug design]] | ||
| + | [[Category: Gpcr]] | ||
| + | [[Category: Lcp-sfx]] | ||
| + | [[Category: Ligand exchange]] | ||
| + | [[Category: Luf5843]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: Sbdd]] | ||
| + | [[Category: Xfel]] | ||
| + | [[Category: Zm241385]] | ||
Revision as of 11:09, 13 November 2019
XFEL A2aR structure by ligand exchange from LUF5843 to ZM241385.
| |||||||||||
Categories: Large Structures | Batyuk, A | Cherezov, C | Gati, C | Han, G W | Ishchenko, A | Iwata, S | Joti, Y | Li, C | Liu, W | Moraes, I | Nakane, T | Nango, E | Shiriaeva, A | Stauch, B | Tanaka, R | Tono, K | Weierstall, U | Zatsepin, N A | A2aar | Complex-lcp method | Drug design | Gpcr | Lcp-sfx | Ligand exchange | Luf5843 | Membrane protein | Sbdd | Xfel | Zm241385
