Sandbox Reserved 1581

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 6: Line 6:
== Function ==
== Function ==
-
Thiamine pyrophosphate is also known as TPP. TPP is essential in all three domains of life, including: bacteria, fungi, and plants. <ref>PMID:16728979</ref> They use this specific riboswitch to control genes that are in charge of synthesizing thiamine and any phosphorylated derivatives.<ref>PMID:16728979</ref> Thiamine pyrophosphate is the most widely distributed riboswitch of the metabolite-sensing RNA regulatory system. <ref>PMID:16728979</ref> The reason for this is because TPP is a form of vitamin B1, and vitamin B1 takes an essential part in many protein-catalyzed reactions; thus it is used quite often.
+
Riboswitches are body-sensing RNAs, that are usually found within non-coding portions of messenger RNAs. <ref>PMID:16728979</ref> Thiamine pyrophosphate is also known as TPP. TPP is essential in all three domains of life, including: bacteria, fungi, and plants. <ref>PMID:16728979</ref> They use this specific riboswitch to control genes that are in charge of synthesizing thiamine and any phosphorylated derivatives.<ref>PMID:16728979</ref> Thiamine pyrophosphate is the most widely distributed riboswitch of the metabolite-sensing RNA regulatory system. <ref>PMID:16728979</ref> The reason for this is because TPP is a form of vitamin B1, and vitamin B1 takes an essential part in many protein-catalyzed reactions; thus it is used quite often.

Revision as of 14:13, 19 November 2019

This Sandbox is Reserved from September 14, 2021, through May 31, 2022, for use in the class Introduction to Biochemistry taught by User:John Means at the University of Rio Grande, Rio Grande, OH, USA. This reservation includes 5 reserved sandboxes (Sandbox Reserved 1590 through Sandbox Reserved 1594).
To get started:
  • Click the edit this page tab at the top. Save the page after each step, then edit it again.
  • Click the 3D button (when editing, above the wikitext box) to insert Jmol.
  • show the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
  • Add a description of your scene. Use the buttons above the wikitext box for bold, italics, links, headlines, etc.

More help: Help:Editing. For an example of a student Proteopedia page, please see Photosystem II, Tetanospasmin, or Guanine riboswitch.

Your Heading Here (maybe something like 'Structure')

TPP Riboswitch

Drag the structure with the mouse to rotate

References

  1. ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. ↑ Serganov A, Polonskaia A, Phan AT, Breaker RR, Patel DJ. Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch. Nature. 2006 Jun 29;441(7097):1167-71. Epub 2006 May 21. PMID:16728979 doi:http://dx.doi.org/nature04740
  3. ↑ Serganov A, Polonskaia A, Phan AT, Breaker RR, Patel DJ. Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch. Nature. 2006 Jun 29;441(7097):1167-71. Epub 2006 May 21. PMID:16728979 doi:http://dx.doi.org/nature04740
  4. ↑ Serganov A, Polonskaia A, Phan AT, Breaker RR, Patel DJ. Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch. Nature. 2006 Jun 29;441(7097):1167-71. Epub 2006 May 21. PMID:16728979 doi:http://dx.doi.org/nature04740
  5. ↑ Serganov A, Polonskaia A, Phan AT, Breaker RR, Patel DJ. Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch. Nature. 2006 Jun 29;441(7097):1167-71. Epub 2006 May 21. PMID:16728979 doi:http://dx.doi.org/nature04740
  6. ↑ Serganov A, Polonskaia A, Phan AT, Breaker RR, Patel DJ. Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch. Nature. 2006 Jun 29;441(7097):1167-71. Epub 2006 May 21. PMID:16728979 doi:http://dx.doi.org/nature04740
  7. ↑ Serganov A, Polonskaia A, Phan AT, Breaker RR, Patel DJ. Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch. Nature. 2006 Jun 29;441(7097):1167-71. Epub 2006 May 21. PMID:16728979 doi:http://dx.doi.org/nature04740
Retrieved from "http://52.214.119.220/wiki/index.php/Sandbox_Reserved_1581"
Personal tools