Sandbox GGC5
From Proteopedia
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==FABP3 with myristic acid== | ==FABP3 with myristic acid== | ||
<StructureSection load='78/781193/Overall/1'</scene> | <StructureSection load='78/781193/Overall/1'</scene> | ||
| - | Heart-type Fatty acid-binding proteins (FABP3) are cytoplasmic carrier protein that active fatty acid metabolism in the heart; found in cardiomyocytes | + | Heart-type Fatty acid-binding proteins (H-FABP/FABP3) are cytoplasmic carrier protein that active fatty acid metabolism in the heart; found in cardiomyocytes. |
| - | + | ||
== Function == | == Function == | ||
| - | Myristic acid <br /> | + | Heart-type fatty acid binding protein (H-FABP) found in heart and skeletal muscle tissue. FABP3 involved in fatty acid metabolism by myristic acid. |
| - | Hexaethylene glycol | + | Myristic acid is long saturated fatty acid chain that found in plant and animal, especially in milk fat. It produced during human metabolism and binds with FAPB3.<br /> |
| + | Hexaethylene glycol used in crystallized FABP3 with myristic acid. | ||
== Disease == | == Disease == | ||
| - | Pulmonary Embolism <br /> | + | Pulmonary Embolism is lung disease that occurs when blood clots block the one of the pulmonary arteries. It blocks blood and oxygen flow and can causes pulmonary infarction when it gets severe. <br /> |
| - | Acute Myocardial Infarction | + | Acute Myocardial Infarction is heart attack that due to cholesterol, saturated fat, and trans-fat build plaque and block the arteries which causes cardio tissue damage. |
== Structure == | == Structure == | ||
Revision as of 07:33, 20 November 2019
FABP3 with myristic acid
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References
<references/Matsuoka, Shigeru, et al. “Water-Mediated Recognition of Simple Alkyl Chains by Heart-Type Fatty-Acid-Binding Protein.” Angewandte Chemie International Edition, vol. 54, no. 5, 2014, pp. 1508–1511., doi:10.1002/anie.201409830.> <references/Myristic acid and Lauric acid. https://www.acs.org/content/acs/en/molecule-of-the-week/archive/m/myristic-acid.html (accessed Nov 6, 2019).> <references/National Center for Biotechnology Information. PubChem Database. Myristic acid, CID=11005, https://pubchem.ncbi.nlm.nih.gov/compound/Myristic-acid (accessed on Nov. 6, 2019)> <references/Mechanic, O. J. (2019, August 15). Acute Myocardial Infarction. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK459269/.> <references/Pulmonary embolism. (2018, March 7). Retrieved from https://www.mayoclinic.org/diseases conditions/pulmonary-embolism/symptoms-causes/syc-20354647.>
