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Sandbox Reserved 1581

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== Function ==
== Function ==
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Riboswitches regulate the synthesis of proteins and are controlled by thiamine pyrophosphate.<ref name= "ghost"> PMID:16728979 </ref> They are usually found within non-coding portions of messenger RNAs.<ref name="ghost" />Thiamine pyrophosphate is also known as TPP. TPP is essential in all three domains of life, including: bacteria, fungi, and plants. <ref name="ghost" /> They use this specific riboswitch to control genes that are in charge of synthesizing thiamine and any phosphorylated derivatives.<ref name="ghost" />TPP and its riboswitch work together to directly regulate the synthesis of a protein related to TPP. <ref name="ghost" />Thiamine pyrophosphate is the most widely distributed riboswitch of the metabolite-sensing RNA regulatory system. <ref name="ghost" /> The reason for this is because TPP is a form of vitamin B1, and vitamin B1 takes an essential part in many protein-catalyzed reactions; thus it is used quite often.
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Riboswitches regulate the synthesis of proteins and are controlled by thiamine pyrophosphate.<ref name= "ghost"> PMID:16728979 </ref> They are usually found within non-coding portions of messenger RNAs.<ref name="ghost" />Thiamine pyrophosphate is also known as TPP. TPP is essential in all three domains of life, including: bacteria, fungi, and plants. <ref name="ghost" /> They use this specific riboswitch to control genes that are in charge of synthesizing thiamine and any phosphorylated derivatives.<ref name="ghost" />TPP and its riboswitch work together to directly regulate the synthesis of a protein related to TPP. <ref name="ghost" />Thiamine pyrophosphate is the most widely distributed riboswitch of the metabolite-sensing RNA regulatory system. <ref name="ghost" /> The reason for this is because TPP is a form of vitamin B1, and vitamin B1 takes an essential part in many protein-catalyzed reactions; thus it is used quite often. zack is right
Magnesium Link <scene name='82/824626/Ahhh/2'>G60 and G78</scene>
Magnesium Link <scene name='82/824626/Ahhh/2'>G60 and G78</scene>

Revision as of 17:44, 20 November 2019

This Sandbox is Reserved from September 14, 2021, through May 31, 2022, for use in the class Introduction to Biochemistry taught by User:John Means at the University of Rio Grande, Rio Grande, OH, USA. This reservation includes 5 reserved sandboxes (Sandbox Reserved 1590 through Sandbox Reserved 1594).
To get started:
  • Click the edit this page tab at the top. Save the page after each step, then edit it again.
  • Click the 3D button (when editing, above the wikitext box) to insert Jmol.
  • show the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
  • Add a description of your scene. Use the buttons above the wikitext box for bold, italics, links, headlines, etc.

More help: Help:Editing. For an example of a student Proteopedia page, please see Photosystem II, Tetanospasmin, or Guanine riboswitch.

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TPP Riboswitch

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References

  1. ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. ↑ Serganov A, Polonskaia A, Phan AT, Breaker RR, Patel DJ. Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch. Nature. 2006 Jun 29;441(7097):1167-71. Epub 2006 May 21. PMID:16728979 doi:http://dx.doi.org/nature04740
  3. ↑ 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 Serganov A, Polonskaia A, Phan AT, Breaker RR, Patel DJ. Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch. Nature. 2006 Jun 29;441(7097):1167-71. Epub 2006 May 21. PMID:16728979 doi:http://dx.doi.org/nature04740
  4. ↑ Serganov A, Polonskaia A, Phan AT, Breaker RR, Patel DJ. Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch. Nature. 2006 Jun 29;441(7097):1167-71. Epub 2006 May 21. PMID:16728979 doi:http://dx.doi.org/nature04740
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