Phosphotransferase
From Proteopedia
(Difference between revisions)
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**[[3sgc]], [[3n4t]], [[3n4u]], [[3n4v]] ,[[4dbx]], [[4de4]] - EncAGPT ID – ''Enterococcus casseliflavus''<BR /> | **[[3sgc]], [[3n4t]], [[3n4u]], [[3n4v]] ,[[4dbx]], [[4de4]] - EncAGPT ID – ''Enterococcus casseliflavus''<BR /> | ||
**[[1j7i]] - EfAGPT IIIA <br /> | **[[1j7i]] - EfAGPT IIIA <br /> | ||
| - | **[[4h05]] – PT VIII – ''Streptomyces rimosus''<br /> | + | **[[4h05]], [[6fuc]] – PT VIII – ''Streptomyces rimosus''<br /> |
**[[4pdy]] – PT – ''Alicyclobacillus acidocaldarius''<br /> | **[[4pdy]] – PT – ''Alicyclobacillus acidocaldarius''<br /> | ||
| + | **[[6ef6]] – PT – ''Mycobacterium smegmatis''<br /> | ||
*Aminoglycoside phosphotransferase complex with nucleotide | *Aminoglycoside phosphotransferase complex with nucleotide | ||
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**[[3sg8]], [[3sg9]], [[4dfb]], [[4dfu]] - EncAGPT ID + antibiotic<br /> | **[[3sg8]], [[3sg9]], [[4dfb]], [[4dfu]] - EncAGPT ID + antibiotic<br /> | ||
**[[3i0o]] - LpAGPT IA + ADP + antibiotic<br /> | **[[3i0o]] - LpAGPT IA + ADP + antibiotic<br /> | ||
| - | **[[4feu]], [[4fev]], [[4few]], [[4fex]], [[4gkh]], [[4gki]] - LpAGPT IA + inhibitor + antibiotic | + | **[[4feu]], [[4fev]], [[4few]], [[4fex]], [[4gkh]], [[4gki]] - LpAGPT IA + inhibitor + antibiotic<br /> |
| + | **[[6fux]] - SrAGPT + ADP + antibiotic<br /> | ||
*Aminoglycoside phosphotransferase complex with inhibitor | *Aminoglycoside phosphotransferase complex with inhibitor | ||
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**[[2jvi]], [[2jvj]], [[2jvk]] - BsPT Spo0F (mutant) – NMR<br /> | **[[2jvi]], [[2jvj]], [[2jvk]] - BsPT Spo0F (mutant) – NMR<br /> | ||
**[[3q15]] - BsPT spo0F + response regulator aspartate phosphatase<br /> | **[[3q15]] - BsPT spo0F + response regulator aspartate phosphatase<br /> | ||
| + | **[[6ifh]] – SpoF - ''Paenisporosarcina''<br /> | ||
*'''Microlide 2”-phosphotransferase''' | *'''Microlide 2”-phosphotransferase''' | ||
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**[[5ih0]] – EcMPT II (mutant) + antibiotic + GDP<br /> | **[[5ih0]] – EcMPT II (mutant) + antibiotic + GDP<br /> | ||
| - | *''' | + | *'''Polyphosphate:AMP phosphotransferase or polyphosphate kinase''' |
**[[5lc9]] – MrPAPT – ''Meiothermus ruber'' <br /> | **[[5lc9]] – MrPAPT – ''Meiothermus ruber'' <br /> | ||
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**[[5o6m]] – MrPAPT (mutant) + ATP <br /> | **[[5o6m]] – MrPAPT (mutant) + ATP <br /> | ||
**[[5ldb]], [[5maq]] – MrPAPT + ADP <br /> | **[[5ldb]], [[5maq]] – MrPAPT + ADP <br /> | ||
| + | **[[6dzg]] – PAPT + ADP – ''Rhizobium meliloti''<br /> | ||
| + | **[[6au0]], [[6aqn]] – ChPAPT + inhibitor – ''Cytophaga hutchinsonii'' <br /> | ||
| + | **[[6anh]] – ChPAPT + guanosine tetraphosphate <br /> | ||
| + | **[[6ang]] – ChPAPT + AMP <br /> | ||
| + | **[[6an9]] – ChPAPT + ADP <br /> | ||
*Rifampin phosphotransferase | *Rifampin phosphotransferase | ||
Revision as of 09:58, 21 November 2019
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3D structures of phosphotransferase
Updated on 21-November-2019
References
- ↑ Wright GD, Thompson PR. Aminoglycoside phosphotransferases: proteins, structure, and mechanism. Front Biosci. 1999 Jan 1;4:D9-21. PMID:9872733
- ↑ Mizrachi Nebenzahl Y, Blau K, Kushnir T, Shagan M, Portnoi M, Cohen A, Azriel S, Malka I, Adawi A, Kafka D, Dotan S, Guterman G, Troib S, Fishilevich T, Gershoni JM, Braiman A, Mitchell AM, Mitchell TJ, Porat N, Goliand I, Chalifa Caspi V, Swiatlo E, Tal M, Ellis R, Elia N, Dagan R. Streptococcus pneumoniae Cell-Wall-Localized Phosphoenolpyruvate Protein Phosphotransferase Can Function as an Adhesin: Identification of Its Host Target Molecules and Evaluation of Its Potential as a Vaccine. PLoS One. 2016 Mar 18;11(3):e0150320. doi: 10.1371/journal.pone.0150320., eCollection 2016. PMID:26990554 doi:http://dx.doi.org/10.1371/journal.pone.0150320
- ↑ Trach K, Burbulys D, Strauch M, Wu JJ, Dhillon N, Jonas R, Hanstein C, Kallio P, Perego M, Bird T, et al.. Control of the initiation of sporulation in Bacillus subtilis by a phosphorelay. Res Microbiol. 1991 Sep-Oct;142(7-8):815-23. PMID:1664534
- ↑ Noguchi N, Takada K, Katayama J, Emura A, Sasatsu M. Regulation of transcription of the mph(A) gene for macrolide 2'-phosphotransferase I in Escherichia coli: characterization of the regulatory gene mphR(A). J Bacteriol. 2000 Sep;182(18):5052-8. PMID:10960087
- ↑ Shiba T, Itoh H, Kameda A, Kobayashi K, Kawazoe Y, Noguchi T. Polyphosphate:AMP phosphotransferase as a polyphosphate-dependent nucleoside monophosphate kinase in Acinetobacter johnsonii 210A. J Bacteriol. 2005 Mar;187(5):1859-65. PMID:15716459 doi:http://dx.doi.org/10.1128/JB.187.5.1859-1865.2005
- ↑ Young PG, Walanj R, Lakshmi V, Byrnes LJ, Metcalf P, Baker EN, Vakulenko SB, Smith CA. The crystal structures of substrate and nucleotide complexes of Enterococcus faecium aminoglycoside-2-phosphotransferase-IIa [APH(2)-IIa] provide insights into substrate selectivity in the APH(2) subfamily. J Bacteriol. 2009 Jul;191(13):4133-43. Epub 2009 May 8. PMID:19429619 doi:10.1128/JB.00149-09
