6l6h
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Lpg0189== | |
| + | <StructureSection load='6l6h' size='340' side='right'caption='[[6l6h]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6l6h]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L6H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6L6H FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6l6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l6h OCA], [http://pdbe.org/6l6h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6l6h RCSB], [http://www.ebi.ac.uk/pdbsum/6l6h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6l6h ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Lpg0189 is a type II secretion system-dependent extracellular protein with unknown function from Legionella pneumophila. Herein, we determined the crystal structure of Lpg0189 at 1.98A resolution by using single-wavelength anomalous diffraction (SAD). Lpg0189 folds into a novel chair-shaped architecture, with two sheets roughly perpendicular to each other. Bioinformatics analysis suggests Lpg0189 and its homologues are unique to Legionellales and evolved divergently. The interlinking structural and bioinformatics studies provide a better understanding of this hypothetical protein. | ||
| - | + | Crystal structure of a hypothetical T2SS effector Lpg0189 from Legionella pneumophila reveals a novel protein fold.,Chen X, Liu S, Jiang S, Zhang X, Zhang N, Ma J, Ge H Biochem Biophys Res Commun. 2019 Nov 6. pii: S0006-291X(19)32111-4. doi:, 10.1016/j.bbrc.2019.10.195. PMID:31706575<ref>PMID:31706575</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 6l6h" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen, X]] | ||
| + | [[Category: Ge, H]] | ||
| + | [[Category: Legionella pneumophila]] | ||
| + | [[Category: Lpg0189]] | ||
| + | [[Category: Novel fold]] | ||
| + | [[Category: T2ss effector]] | ||
| + | [[Category: Unknown function]] | ||
Revision as of 06:48, 27 November 2019
Crystal structure of Lpg0189
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