196d
From Proteopedia
Revision as of 06:35, 2 May 2008
CRYSTAL STRUCTURE OF C-T-C-T-C-G-A-G-A-G: IMPLICATIONS FOR THE STRUCTURE OF THE HOLLIDAY JUNCTION
Overview
The structure of the B-DNA decamer of sequence C-T-C-T-C-G-A-G-A-G shows a crossed arrangement of helices in the C2 crystal lattice. This is the fourth example of a crossed arrangement of B-DNA oligomers in a crystal, and in spite of the fact that each of these four crystallizes in a different lattice, all have nearly identical structures at the crossing contact. This ubiquitous crossing arrangement may be used to generate a structure for the Holliday junction that is fully consistent with the available physical data.
About this Structure
Full crystallographic information is available from OCA.
Reference
Crystal structure of C-T-C-T-C-G-A-G-A-G. Implications for the structure of the Holliday junction., Goodsell DS, Grzeskowiak K, Dickerson RE, Biochemistry. 1995 Jan 24;34(3):1022-9. PMID:7827018 Page seeded by OCA on Fri May 2 09:35:40 2008
