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Pre-mRNA-splicing factor

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Line 65: Line 65:
**[[4kit]] – yPrp Jab1/MPN domain + U5 small nuclear ribonucleoprotein helicase <br />
**[[4kit]] – yPrp Jab1/MPN domain + U5 small nuclear ribonucleoprotein helicase <br />
**[[4ilg]] – yPrp Jab1/MPN+RNA-binding domains + A1 cistron-splicing factor AAR2 <br />
**[[4ilg]] – yPrp Jab1/MPN+RNA-binding domains + A1 cistron-splicing factor AAR2 <br />
 +
**[[6nqi]] – Prp RH domain – red alga <br />
**[[2p8r]] – CePrp C terminal (mutant) – ''Caenorhabditis elegans''<br />
**[[2p8r]] – CePrp C terminal (mutant) – ''Caenorhabditis elegans''<br />
**[[2p87]] – CePrp C terminal <br />
**[[2p87]] – CePrp C terminal <br />
 +
**[[6mwy]] – Prp – ''Cryptococcus gattii'' <br />
*Pre-mRNA-splicing factor 9
*Pre-mRNA-splicing factor 9
Line 125: Line 127:
*Pre-mRNA-splicing factors in spliceosome
*Pre-mRNA-splicing factors in spliceosome
-
**[[3jcr]], [[5o9z]] – hPrp - CryoEM<br />
+
**[[3jcr]], [[5o9z]], [[6id1]], [[6id0]], [[6icz]], [[6ff7]], [[6ff4]], [[6ah0]], [[5z58]] – hPrp - CryoEM<br />
**[[3jb9]] – yPrp <br />
**[[3jb9]] – yPrp <br />
-
**[[3jcm]], [[5gam]], [[5gan]], [[5gao]], [[5gap]], [[5gmk]], [[5lj3]], [[5lj5]], [[5lqw]], [[5mps]], [[5mq0]], [[5mqf]], [[5wsg]], [[6g90]], [[6exn]], [[6bk8]], [[5ylz]], [[5y88]] – yPrp - CryoEM<br />
+
**[[3jcm]], [[5gam]], [[5gan]], [[5gao]], [[5gap]], [[5gmk]], [[5lj3]], [[5lj5]], [[5lqw]], [[5mps]], [[5mq0]], [[5mqf]], [[5wsg]], [[6g90]], [[6exn]], [[6bk8]], [[5ylz]], [[5y88]], [[6j6q]], [[6j6n]], [[6j6h]], [[6j6g]], [[5zwo]] – yPrp - CryoEM<br />
*Pre-mRNA-splicing factor cwc2
*Pre-mRNA-splicing factor cwc2

Revision as of 09:16, 27 November 2019

Yeast pre-mRNA-splicing factor 8 (green) complex with AAR2 (cyan) (PDB entry 3zef)

Drag the structure with the mouse to rotate

3D Structures of pre-mRNA splicing factors

Updated on 27-November-2019



References

  1. ↑ Misteli T, Spector DL. RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo. Mol Cell. 1999 Jun;3(6):697-705. PMID:10394358
  2. ↑ McKie AB, McHale JC, Keen TJ, Tarttelin EE, Goliath R, van Lith-Verhoeven JJ, Greenberg J, Ramesar RS, Hoyng CB, Cremers FP, Mackey DA, Bhattacharya SS, Bird AC, Markham AF, Inglehearn CF. Mutations in the pre-mRNA splicing factor gene PRPC8 in autosomal dominant retinitis pigmentosa (RP13). Hum Mol Genet. 2001 Jul 15;10(15):1555-62. PMID:11468273

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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