Pregnane X receptor
From Proteopedia
(Difference between revisions)
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**[[4j5w]] – hPXR LBD + hRXR LBD<br /> | **[[4j5w]] – hPXR LBD + hRXR LBD<br /> | ||
| - | *Pregnane X receptor complex | + | *Pregnane X receptor complex |
**[[1ilh]], [[2qnv]] – hPXR LBD + ligand<br /> | **[[1ilh]], [[2qnv]] – hPXR LBD + ligand<br /> | ||
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**[[1skx]] – hPXR LBD + antibiotic<br /> | **[[1skx]] – hPXR LBD + antibiotic<br /> | ||
**[[3r8d]] – hPXR LBD + anti-HIV drug<br /> | **[[3r8d]] – hPXR LBD + anti-HIV drug<br /> | ||
| - | **[[1nrl]], [[2o9i]], [[5a86]] – hPXR LBD + nuclear receptor coactivator peptide + ligand<br /> | + | **[[1nrl]], [[2o9i]], [[5a86]], [[5x0r]] – hPXR LBD + nuclear receptor coactivator peptide + ligand<br /> |
**[[4j5x]] – hPXR LBD + hRXR LBD + ligand<br /> | **[[4j5x]] – hPXR LBD + hRXR LBD + ligand<br /> | ||
**[[3hvl]] – hPXR/steroid receptor coactivator + ligand<br /> | **[[3hvl]] – hPXR/steroid receptor coactivator + ligand<br /> | ||
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**[[4x1f]], [[4x1g]] – hPXR LBD + estrogen derivative<br /> | **[[4x1f]], [[4x1g]] – hPXR LBD + estrogen derivative<br /> | ||
**[[4xao]] – hPXR LBD + pesticide<br /> | **[[4xao]] – hPXR LBD + pesticide<br /> | ||
| - | + | **[[6s41]], [[6dup]] – hPXR LBD + inhibitor<br /> | |
}} | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 09:25, 27 November 2019
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3D structures of pregnane X receptor
Updated on 27-November-2019
References
- ↑ Kliewer SA, Goodwin B, Willson TM. The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism. Endocr Rev. 2002 Oct;23(5):687-702. PMID:12372848 doi:http://dx.doi.org/10.1210/er.2001-0038
- ↑ Koutsounas I, Theocharis S, Patsouris E, Giaginis C. Pregnane X receptor (PXR) at the crossroads of human metabolism and disease. Curr Drug Metab. 2013 Mar;14(3):341-50. PMID:23237007
- ↑ Chrencik JE, Orans J, Moore LB, Xue Y, Peng L, Collins JL, Wisely GB, Lambert MH, Kliewer SA, Redinbo MR. Structural disorder in the complex of human pregnane X receptor and the macrolide antibiotic rifampicin. Mol Endocrinol. 2005 May;19(5):1125-34. Epub 2005 Feb 10. PMID:15705662 doi:10.1210/me.2004-0346
