Protein kinase C
From Proteopedia
(Difference between revisions)
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*'''Atypical PKC''' | *'''Atypical PKC''' | ||
| - | *PKC-ι | + | *PKC-ι; domains – PB1 16-99; kinase 249-588 |
| - | **[[1vd2]] – hAPKC-ι PB1 domain – NMR | + | **[[1vd2]] – hAPKC-ι PB1 domain – NMR<br /> |
| - | + | **[[1wmh]] - hAPKC-ι PB1 domain + PAR6 alpha<br /> | |
| - | **[[ | + | **[[3a8w]], [[3a8x]], [[1zrz]] - hAPKC-ι kinase domain<br /> |
| - | + | **[[6ilz]] - hAPKC-ι kinase domain + inhibitor<br /> | |
| - | **[[3a8w]], [[3a8x]] - hAPKC-ι kinase domain<br /> | + | |
**[[3zh8]] - hAPKC-ι kinase domain (mutant) + inhibitor<br /> | **[[3zh8]] - hAPKC-ι kinase domain (mutant) + inhibitor<br /> | ||
**[[1wmh]] - hAPKC-ι PB1 domain + PAR6 alpha<br /> | **[[1wmh]] - hAPKC-ι PB1 domain + PAR6 alpha<br /> | ||
| - | **[[4dc2]] - hAPKC-ι | + | **[[4dc2]] - hAPKC-ι kinase domain + PAR3 peptide<br /> |
**[[5lih]] - hAPKC-ι kinase domain + PKC-εζ peptide<br /> | **[[5lih]] - hAPKC-ι kinase domain + PKC-εζ peptide<br /> | ||
Revision as of 07:37, 1 December 2019
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3D structures of protein kinase C
Updated on 01-December-2019
References
- ↑ Idris I, Gray S, Donnelly R. Protein kinase C activation: isozyme-specific effects on metabolism and cardiovascular complications in diabetes. Diabetologia. 2001 Jun;44(6):659-73. PMID:11440359 doi:http://dx.doi.org/10.1007/s001250051675
- ↑ Koya D, King GL. Protein kinase C activation and the development of diabetic complications. Diabetes. 1998 Jun;47(6):859-66. PMID:9604860
- ↑ Koivunen J, Aaltonen V, Peltonen J. Protein kinase C (PKC) family in cancer progression. Cancer Lett. 2006 Apr 8;235(1):1-10. PMID:15907369 doi:http://dx.doi.org/10.1016/j.canlet.2005.03.033
- ↑ Guerrero-Valero M, Ferrer-Orta C, Querol-Audi J, Marin-Vicente C, Fita I, Gomez-Fernandez JC, Verdaguer N, Corbalan-Garcia S. Structural and mechanistic insights into the association of PKC{alpha}-C2 domain to PtdIns(4,5)P2. Proc Natl Acad Sci U S A. 2009 Apr 3. PMID:19346474
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