1a0i

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1a0i.gif|left|200px]]
[[Image:1a0i.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1a0i |SIZE=350|CAPTION= <scene name='initialview01'>1a0i</scene>, resolution 2.6&Aring;
+
The line below this paragraph, containing "STRUCTURE_1a0i", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=ATP:ADENOSINE-5&#39;-TRIPHOSPHATE'>ATP</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_ligase_(ATP) DNA ligase (ATP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.1 6.5.1.1] </span>
+
or leave the SCENE parameter empty for the default display.
-
|GENE= LIG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10760 Enterobacteria phage T7])
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1a0i| PDB=1a0i | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a0i OCA], [http://www.ebi.ac.uk/pdbsum/1a0i PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1a0i RCSB]</span>
+
-
}}
+
'''ATP-DEPENDENT DNA LIGASE FROM BACTERIOPHAGE T7 COMPLEX WITH ATP'''
'''ATP-DEPENDENT DNA LIGASE FROM BACTERIOPHAGE T7 COMPLEX WITH ATP'''
Line 24: Line 21:
Crystal structure of an ATP-dependent DNA ligase from bacteriophage T7., Subramanya HS, Doherty AJ, Ashford SR, Wigley DB, Cell. 1996 May 17;85(4):607-15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8653795 8653795]
Crystal structure of an ATP-dependent DNA ligase from bacteriophage T7., Subramanya HS, Doherty AJ, Ashford SR, Wigley DB, Cell. 1996 May 17;85(4):607-15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8653795 8653795]
[[Category: DNA Ligase]]
[[Category: DNA Ligase]]
-
[[Category: DNA ligase (ATP)]]
 
[[Category: Enterobacteria phage t7]]
[[Category: Enterobacteria phage t7]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 31: Line 27:
[[Category: Subramanya, H S.]]
[[Category: Subramanya, H S.]]
[[Category: Wigley, D B.]]
[[Category: Wigley, D B.]]
-
[[Category: dna replication]]
+
[[Category: Dna replication]]
-
[[Category: ligase]]
+
[[Category: Ligase]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 09:37:36 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 18:30:32 2008''
+

Revision as of 06:37, 2 May 2008

Image:1a0i.gif

Template:STRUCTURE 1a0i

ATP-DEPENDENT DNA LIGASE FROM BACTERIOPHAGE T7 COMPLEX WITH ATP


Overview

The crystal structure of the ATP-dependent DNA ligase from bacteriophage T7 has been solved at 2.6 A resolution. The protein comprises two domains with a deep cleft running between them. The structure of a complex with ATP reveals that the nucleotide binding pocket is situated on the larger N-terminal domain, at the base of the cleft between the two domains of the enzyme. Comparison of the overall domain structure with that of DNA methyltransferases, coupled with other evidence, suggests that DNA also binds in this cleft. Since this structure is the first of the nucleotidyltransferase superfamily, which includes the eukaryotic mRNA capping enzymes, the relationship between the structure of DNA ligase and that of other nucleotidyltransferases is also discussed.

About this Structure

1A0I is a Single protein structure of sequence from Enterobacteria phage t7. The following page contains interesting information on the relation of 1A0I with [DNA Ligase]. Full crystallographic information is available from OCA.

Reference

Crystal structure of an ATP-dependent DNA ligase from bacteriophage T7., Subramanya HS, Doherty AJ, Ashford SR, Wigley DB, Cell. 1996 May 17;85(4):607-15. PMID:8653795 Page seeded by OCA on Fri May 2 09:37:36 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1a0i"
Personal tools