Protein phosphatase
From Proteopedia
(Difference between revisions)
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</StructureSection> | </StructureSection> | ||
| - | == 3D Structures of protein phosphatase== | ||
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| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| - | *Protein phosphatase 1 | ||
| - | **[[2rlt]] - PP1 regulatory subunit - pig - NMR<br /> | ||
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| - | *Protein phosphatase 1A | ||
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| - | **[[3fxj]], [[3fxk]], [[3fxl]], [[3fxm]], [[3fxo]], [[4ra2]] – hPP1A + Mn – human<br /> | ||
| - | **[[3n5u]] – hPP1A catalytic subunit + retinoblastoma-associated protein<br /> | ||
| - | **[[4g9j]], [[5ioh]] – hPP1A catalytic subunit + peptide<br /> | ||
| - | **[[6b67]] – hPP1A catalytic subunit (mutant) + peptide<br /> | ||
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| - | *Protein phosphatase 1G | ||
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| - | **[[5inb]], [[5j28]] - hPP1G catalytic subunit + peptide<br /> | ||
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| - | *Protein phosphatase 1K | ||
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| - | **[[4da1]] - hPP1K + Mn<br /> | ||
| - | **[[6ak7]] – hPP1K (mutant) + Mg<br /> | ||
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| - | *Protein phosphatase 2A or serine/threonine-protein phosphatase 2A | ||
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| - | **[[1b3u]], [[2g62]], [[2hv6]], [[4mew]], [[4i5k]], [[4i5j]], [[2jak]], [[2ixm]], [[2hv7] – hPP2A regulatory subunit <br /> | ||
| - | **[[5swf]], [[5k6s]], [[5jja]] – hPP2A regulatory subunit + BUBR1<br /> | ||
| - | **[[5sw9]] – hPP2A regulatory subunit + REPOMAN<br /> | ||
| - | **[[2pkg]], [[2pf4]] – hPP2A regulatory subunit + small T antigen<br /> | ||
| - | **[[2ie3]], [[2ie4]], [[2npp]], [[2nyl]], [[2nym]] – hPP2A catalytic + regulatory subunit + tumor-inducing toxin<br /> | ||
| - | **[[3c5w]] – hPP2A catalytic + regulatory subunit + PP2A-specific methyltransferase<br /> | ||
| - | **[[3p71]], [[2iae]] – hPP2A catalytic + regulatory subunit + LCMT-1 <br /> | ||
| - | **[[3dw8]] – hPP2A catalytic + regulatory subunit (mutant) + LCMT-1 <br /> | ||
| - | **[[3fga]] – hPP2A catalytic + regulatory subunit + LCMT-1 + SGO<br /> | ||
| - | **[[4i5n]], [[4i5l]] – hPP2A catalytic + regulatory subunit + MCLR<br /> | ||
| - | **[[3k7w]] – hPP2A catalytic + regulatory subunit + toxin<br /> | ||
| - | **[[4iyp]] – hPP2A catalytic subunit + immunoglobin-binding protein<br /> | ||
| - | **[[6ef4]] – mPP2A (mutant) - mouse<br /> | ||
| - | **[[5w0w]] – mPP2A + TIPRL<br /> | ||
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| - | *Protein phosphatase 2B See [[Calcineurin]] | ||
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| - | *Protein phosphatase 2C | ||
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| - | **[[2iq1]] – hPP2C κ <br /> | ||
| - | **[[4raf]], [[4rag]] - hPP2C α (mutant) + Mn<br /> | ||
| - | **[[3d8k]] – PP2C – ''Toxoplasma gondii''<br /> | ||
| - | **[[3ujk]] – AtPP2C - ''Arabidopsis thaliana'' <br /> | ||
| - | **[[4yzg]] – AtPP2C (mutant) <br /> | ||
| - | **[[3jrq]], [[3nmn]] – AtPP2C + Pyl1 + pyrabactin <br /> | ||
| - | **[[3kdj]] - AtPP2C + Pyl1 + abscicic acid<br /> | ||
| - | **[[3nmt]], [[3kb3]], [[3nmv]], [[3ujl]] – AtPP2C + Pyl2<br /> | ||
| - | **[[4la7]], [[4lg5]], [[4lga]], [[4lgb]] – AtPP2C + Pyl2 + ligand<br /> | ||
| - | **[[5vr7]], [[5vro]], [[5vs5]], [[5vsq]], [[5vsr]], [[5vt7]] – AtPP2C + Pyl2 + quinolone derivative<br /> | ||
| - | **[[4ds8]], [[5jo1]], [[5jo2]] – AtPP2C + Pyl3 + Mn<br /> | ||
| - | **[[3rt0]] – AtPP2C (mutant) + Pyl10<br /> | ||
| - | **[[4n0g]] – AtPP2C + Pyl13<br /> | ||
| - | **[[3qn1]], [[3zvu]], [[4wvo]] – AtPP2C + Pyr1<br /> | ||
| - | **[[5or2]], [[5or6]] – AtPP2C + Pyr1 + abscicic acid analog<br /> | ||
| - | **[[4yzh]] – AtPP2C (mutant) + chlorophyll-binding protein peptide<br /> | ||
| - | **[[3ujg]] - AtPP2C + SRK2E<br /> | ||
| - | **[[5mn0]] – AtPP2C + ABA receptor <br /> | ||
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| - | *Protein phosphatase 4 | ||
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| - | **[[4wsf]] – PP4 regulatory subunit + Cenp-C – ''Drosophila melanogaster''<br /> | ||
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| - | *Protein phosphatase 5 | ||
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| - | **[[1wao]] – hPP5 + Mn<br /> | ||
| - | **[[5muf]] – hPP5 <br /> | ||
| - | **[[1a17]] – hPP5 protein-interacting domain<br /> | ||
| - | **[[2bug]] – hPP5 protein-interacting domain (mutant) + Hsp90 peptide - NMR<br /> | ||
| - | **[[1s95]], [[3h60]] – hPP5 catalytic domain + Mn<br /> | ||
| - | **[[3h61]], [[3h62]], [[3h63]], [[3h64]], [[3h66]], [[3h67]], [[3h68]], [[3h69]], [[4zvz]], [[4zx2]], [[4zvz]], [[4zx2]] – hPP5 catalytic domain + inhibitor + Mn<br /> | ||
| - | **[[5hpe]] – hPP5 catalytic domain/Hsp90 peptide + Mn<br /> | ||
| - | **[[4ja7]], [[4ja9]] - rPP5 catalytic domain + inhibitor <br /> | ||
| - | **[[3icf]] - yPP5 catalytic domain + Fe - yeast<br /> | ||
| - | **[[5jjt]] – AtPP5 + Ni<br /> | ||
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| - | *Protein phosphatase | ||
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| - | **[[1g5b]] – PP + Mn – Enterobacteria phage λ<br /> | ||
| - | **[[2pk0]] – PP + Mg – ''Streptococcus agalactiae''<br /> | ||
| - | **[[2cm1]] – PP + Mn – ''Mycobacterium tuberculosis''<br /> | ||
| - | **[[3pu9]] – PP + Mg – ''Sphaerobacter thermophilus''<br /> | ||
| - | **[[5f1m]] – PP Stp1 + Mn – ''Staphylococcus aureus''<br /> | ||
| - | **[[5jpf]] – PP Z1 + microcystin-LR + Mn – ''Candida albicans''<br /> | ||
| - | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 08:38, 2 December 2019
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References
- ↑ Ragolia L, Begum N. Protein phosphatase-1 and insulin action. Mol Cell Biochem. 1998 May;182(1-2):49-58. PMID:9609113
- ↑ Resjo S, Goransson O, Harndahl L, Zolnierowicz S, Manganiello V, Degerman E. Protein phosphatase 2A is the main phosphatase involved in the regulation of protein kinase B in rat adipocytes. Cell Signal. 2002 Mar;14(3):231-8. PMID:11812651
- ↑ Lipinszki Z, Lefevre S, Savoian MS, Singleton MR, Glover DM, Przewloka MR. Centromeric binding and activity of Protein Phosphatase 4. Nat Commun. 2015 Jan 6;6:5894. doi: 10.1038/ncomms6894. PMID:25562660 doi:http://dx.doi.org/10.1038/ncomms6894
- ↑ Chinkers M. Protein phosphatase 5 in signal transduction. Trends Endocrinol Metab. 2001 Jan-Feb;12(1):28-32. PMID:11137038
- ↑ Perrotti D, Neviani P. Protein phosphatase 2A: a target for anticancer therapy. Lancet Oncol. 2013 May;14(6):e229-38. doi: 10.1016/S1470-2045(12)70558-2. PMID:23639323 doi:http://dx.doi.org/10.1016/S1470-2045(12)70558-2
- ↑ Rudrabhatla P, Pant HC. Role of protein phosphatase 2A in Alzheimer's disease. Curr Alzheimer Res. 2011 Sep;8(6):623-32. PMID:21605044
- ↑ Huhn J, Jeffrey PD, Larsen K, Rundberget T, Rise F, Cox NR, Arcus V, Shi Y, Miles CO. A structural basis for the reduced toxicity of dinophysistoxin-2. Chem Res Toxicol. 2009 Nov;22(11):1782-6. PMID:19916524 doi:10.1021/tx9001622
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