1a0t

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[[Image:1a0t.gif|left|200px]]
[[Image:1a0t.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1a0t |SIZE=350|CAPTION= <scene name='initialview01'>1a0t</scene>, resolution 2.4&Aring;
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The line below this paragraph, containing "STRUCTURE_1a0t", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SUC:SUCROSE'>SUC</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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or leave the SCENE parameter empty for the default display.
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|GENE= SCRY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=602 Salmonella typhimurium])
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-->
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|DOMAIN=
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{{STRUCTURE_1a0t| PDB=1a0t | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a0t OCA], [http://www.ebi.ac.uk/pdbsum/1a0t PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1a0t RCSB]</span>
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}}
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'''SUCROSE-SPECIFIC PORIN, WITH BOUND SUCROSE MOLECULES'''
'''SUCROSE-SPECIFIC PORIN, WITH BOUND SUCROSE MOLECULES'''
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[[Category: Diederichs, K.]]
[[Category: Diederichs, K.]]
[[Category: Welte, W.]]
[[Category: Welte, W.]]
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[[Category: outer membrane protein]]
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[[Category: Outer membrane protein]]
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[[Category: porin]]
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[[Category: Porin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 09:38:39 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 18:30:40 2008''
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Revision as of 06:38, 2 May 2008

Image:1a0t.gif

Template:STRUCTURE 1a0t

SUCROSE-SPECIFIC PORIN, WITH BOUND SUCROSE MOLECULES


Overview

The X-ray structure of a sucrose-specific porin (ScrY) from Salmonella typhimurium has been determined by multiple isomorphous replacement at 2.4 A resolution both in its uncomplexed form and with bound sucrose. ScrY is a noncrystallographic trimer of identical subunits, each with 413 structurally well-defined amino acids. A monomer is built up of 18 anti-parallel beta-strands surrounding a hydrophilic pore, with a topology closely similar to that of maltoporin. Two non-overlapping sucrose-binding sites were identified in difference Fourier maps. The higher permeability for sucrose of ScrY as compared to maltoporin is mainly accounted for by differences in their pore-lining residues.

About this Structure

1A0T is a Single protein structure of sequence from Salmonella typhimurium. Full crystallographic information is available from OCA.

Reference

Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose., Forst D, Welte W, Wacker T, Diederichs K, Nat Struct Biol. 1998 Jan;5(1):37-46. PMID:9437428 Page seeded by OCA on Fri May 2 09:38:39 2008

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