6s6y
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==X-ray crystal structure of the formyltransferase/hydrolase complex (FhcABCD) from Methylorubrum extorquens in complex with methylofuran== | |
| - | + | <StructureSection load='6s6y' size='340' side='right'caption='[[6s6y]], [[Resolution|resolution]] 3.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6s6y]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Methylobacterium_extorquens_(strain_pa1) Methylobacterium extorquens (strain pa1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S6Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6S6Y FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IAS:BETA-L-ASPARTIC+ACID'>IAS</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=L6K:(2~{S})-3-[4-[[5-(aminomethyl)furan-3-yl]methoxy]phenyl]-2-(methylamino)propanoic+acid'>L6K</scene>, <scene name='pdbligand=MFN:N-[4,5,7-TRICARBOXYHEPTANOYL]-L-GAMMA-GLUTAMYL-N-{2-[4-({5-[(FORMYLAMINO)METHYL]-3-FURYL}METHOXY)PHENYL]ETHYL}-D-GLUTAMINE'>MFN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Formylmethanofuran--tetrahydromethanopterin_N-formyltransferase Formylmethanofuran--tetrahydromethanopterin N-formyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.101 2.3.1.101] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6s6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6s6y OCA], [http://pdbe.org/6s6y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6s6y RCSB], [http://www.ebi.ac.uk/pdbsum/6s6y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6s6y ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/A9W3R8_METEP A9W3R8_METEP]] Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT).[HAMAP-Rule:MF_00579] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Formylmethanofuran--tetrahydromethanopterin N-formyltransferase]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Hemmann, J L]] | ||
[[Category: Shima, S]] | [[Category: Shima, S]] | ||
| + | [[Category: Vorholt, J]] | ||
[[Category: Wagner, T]] | [[Category: Wagner, T]] | ||
| - | [[Category: | + | [[Category: Channeling]] |
| - | [[Category: | + | [[Category: Formate dehydrogenase]] |
| + | [[Category: Formyl-transferase]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Metallo-hydrolase]] | ||
| + | [[Category: Methylofuran]] | ||
| + | [[Category: Methylotrophy]] | ||
| + | [[Category: Polyglutamate]] | ||
| + | [[Category: Prosthetic group]] | ||
Revision as of 08:19, 4 December 2019
X-ray crystal structure of the formyltransferase/hydrolase complex (FhcABCD) from Methylorubrum extorquens in complex with methylofuran
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Categories: Formylmethanofuran--tetrahydromethanopterin N-formyltransferase | Large Structures | Hemmann, J L | Shima, S | Vorholt, J | Wagner, T | Channeling | Formate dehydrogenase | Formyl-transferase | Hydrolase | Metallo-hydrolase | Methylofuran | Methylotrophy | Polyglutamate | Prosthetic group
