5swp

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==Crystal Structure of PI3Kalpha in complex with fragments 6 and 24==
==Crystal Structure of PI3Kalpha in complex with fragments 6 and 24==
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<StructureSection load='5swp' size='340' side='right' caption='[[5swp]], [[Resolution|resolution]] 3.41&Aring;' scene=''>
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<StructureSection load='5swp' size='340' side='right'caption='[[5swp]], [[Resolution|resolution]] 3.41&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5swp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SWP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5SWP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5swp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SWP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5SWP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=70V:2-METHYLCYCLOHEXANE-1,3-DIONE'>70V</scene>, <scene name='pdbligand=70W:TERT-BUTYL+4-AMINOPIPERIDINE-1-CARBOXYLATE'>70W</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=70V:2-METHYLCYCLOHEXANE-1,3-DIONE'>70V</scene>, <scene name='pdbligand=70W:TERT-BUTYL+4-AMINOPIPERIDINE-1-CARBOXYLATE'>70W</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5sw8|5sw8]], [[5swg|5swg]], [[5swo|5swo]], [[5swr|5swr]], [[5swt|5swt]], [[5sx8|5sx8]], [[5sx9|5sx9]], [[5sxa|5sxa]], [[5sxb|5sxb]], [[5sxc|5sxc]], [[5sxd|5sxd]], [[5sxe|5sxe]], [[5sxf|5sxf]], [[5sxi|5sxi]], [[5sxj|5sxj]], [[5sxk|5sxk]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5sw8|5sw8]], [[5swg|5swg]], [[5swo|5swo]], [[5swr|5swr]], [[5swt|5swt]], [[5sx8|5sx8]], [[5sx9|5sx9]], [[5sxa|5sxa]], [[5sxb|5sxb]], [[5sxc|5sxc]], [[5sxd|5sxd]], [[5sxe|5sxe]], [[5sxf|5sxf]], [[5sxi|5sxi]], [[5sxj|5sxj]], [[5sxk|5sxk]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PIK3CA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), PIK3R1, GRB1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5swp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5swp OCA], [http://pdbe.org/5swp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5swp RCSB], [http://www.ebi.ac.uk/pdbsum/5swp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5swp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5swp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5swp OCA], [http://pdbe.org/5swp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5swp RCSB], [http://www.ebi.ac.uk/pdbsum/5swp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5swp ProSAT]</span></td></tr>
</table>
</table>
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</div>
</div>
<div class="pdbe-citations 5swp" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5swp" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Phosphoinositide 3-kinase 3D structures|Phosphoinositide 3-kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Amzel, L M]]
[[Category: Amzel, L M]]
[[Category: Gabelli, S B]]
[[Category: Gabelli, S B]]

Revision as of 09:19, 4 December 2019

Crystal Structure of PI3Kalpha in complex with fragments 6 and 24

PDB ID 5swp

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