5t37

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==crystal structure of mPGES-1 bound to inhibitor==
==crystal structure of mPGES-1 bound to inhibitor==
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<StructureSection load='5t37' size='340' side='right' caption='[[5t37]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
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<StructureSection load='5t37' size='340' side='right'caption='[[5t37]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5t37]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T37 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T37 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5t37]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T37 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T37 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=758:2-CHLORO-5-{[(2,2-DIMETHYLPROPANOYL)AMINO]METHYL}-N-(1H-IMIDAZOL-2-YL)BENZAMIDE'>758</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=758:2-CHLORO-5-{[(2,2-DIMETHYLPROPANOYL)AMINO]METHYL}-N-(1H-IMIDAZOL-2-YL)BENZAMIDE'>758</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTGES, MGST1L1, MPGES1, PGES, PIG12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Prostaglandin-E_synthase Prostaglandin-E synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.99.3 5.3.99.3] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Prostaglandin-E_synthase Prostaglandin-E synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.99.3 5.3.99.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t37 OCA], [http://pdbe.org/5t37 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t37 RCSB], [http://www.ebi.ac.uk/pdbsum/5t37 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t37 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t37 OCA], [http://pdbe.org/5t37 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t37 RCSB], [http://www.ebi.ac.uk/pdbsum/5t37 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t37 ProSAT]</span></td></tr>
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</div>
</div>
<div class="pdbe-citations 5t37" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5t37" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Prostaglandin E synthase|Prostaglandin E synthase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Prostaglandin-E synthase]]
[[Category: Prostaglandin-E synthase]]
[[Category: Antonysamy, S]]
[[Category: Antonysamy, S]]

Revision as of 09:22, 4 December 2019

crystal structure of mPGES-1 bound to inhibitor

PDB ID 5t37

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