5tl9

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==crystal structure of mPGES-1 bound to inhibitor==
==crystal structure of mPGES-1 bound to inhibitor==
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<StructureSection load='5tl9' size='340' side='right' caption='[[5tl9]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
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<StructureSection load='5tl9' size='340' side='right'caption='[[5tl9]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5tl9]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TL9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TL9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5tl9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TL9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TL9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7DN:2-{2-[(1S,2S)-2-{[1-(8-METHYLQUINOLIN-2-YL)PIPERIDINE-4-CARBONYL]AMINO}CYCLOPENTYL]ETHYL}BENZOIC+ACID'>7DN</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=JZR:HEXYL+BETA-D-GLUCOPYRANOSIDE'>JZR</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7DN:2-{2-[(1S,2S)-2-{[1-(8-METHYLQUINOLIN-2-YL)PIPERIDINE-4-CARBONYL]AMINO}CYCLOPENTYL]ETHYL}BENZOIC+ACID'>7DN</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=JZR:HEXYL+BETA-D-GLUCOPYRANOSIDE'>JZR</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTGES, MGST1L1, MPGES1, PGES, PIG12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Prostaglandin-E_synthase Prostaglandin-E synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.99.3 5.3.99.3] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Prostaglandin-E_synthase Prostaglandin-E synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.99.3 5.3.99.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tl9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tl9 OCA], [http://pdbe.org/5tl9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tl9 RCSB], [http://www.ebi.ac.uk/pdbsum/5tl9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tl9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tl9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tl9 OCA], [http://pdbe.org/5tl9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tl9 RCSB], [http://www.ebi.ac.uk/pdbsum/5tl9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tl9 ProSAT]</span></td></tr>
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</div>
</div>
<div class="pdbe-citations 5tl9" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5tl9" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Prostaglandin E synthase|Prostaglandin E synthase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Prostaglandin-E synthase]]
[[Category: Prostaglandin-E synthase]]
[[Category: Antonysamy, S]]
[[Category: Antonysamy, S]]

Revision as of 09:24, 4 December 2019

crystal structure of mPGES-1 bound to inhibitor

PDB ID 5tl9

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