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6b63
From Proteopedia
(Difference between revisions)
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==IMPase (AF2372) with 25 mM Asp== | ==IMPase (AF2372) with 25 mM Asp== | ||
| - | <StructureSection load='6b63' size='340' side='right' caption='[[6b63]], [[Resolution|resolution]] 2.70Å' scene=''> | + | <StructureSection load='6b63' size='340' side='right'caption='[[6b63]], [[Resolution|resolution]] 2.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6b63]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B63 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B63 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6b63]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arcfu Arcfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B63 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B63 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU7:(2R)-2,3-dihydroxypropyl+(2S)-2,3-dihydroxypropyl+hydrogen+phosphate'>CU7</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU7:(2R)-2,3-dihydroxypropyl+(2S)-2,3-dihydroxypropyl+hydrogen+phosphate'>CU7</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">suhB, AF_2372 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224325 ARCFU])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b63 OCA], [http://pdbe.org/6b63 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b63 RCSB], [http://www.ebi.ac.uk/pdbsum/6b63 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b63 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b63 OCA], [http://pdbe.org/6b63 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b63 RCSB], [http://www.ebi.ac.uk/pdbsum/6b63 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b63 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/BSUHB_ARCFU BSUHB_ARCFU]] Phosphatase with broad specificity; it can dephosphorylate fructose 1,6-bisphosphate, both D and L isomers of inositol-1-phosphate (I-1-P), 2'-AMP, pNPP, inositol-2-phosphate, beta-glycerol phosphate, and alpha-D-glucose-1-phosphate. Cannot hydrolyze glucose-6-phosphate and fructose-6-phosphate. May be involved in the biosynthesis of a unique osmolyte, di-myo-inositol 1,1-phosphate.<ref>PMID:10747806</ref> <ref>PMID:11062561</ref> <ref>PMID:11940584</ref> | [[http://www.uniprot.org/uniprot/BSUHB_ARCFU BSUHB_ARCFU]] Phosphatase with broad specificity; it can dephosphorylate fructose 1,6-bisphosphate, both D and L isomers of inositol-1-phosphate (I-1-P), 2'-AMP, pNPP, inositol-2-phosphate, beta-glycerol phosphate, and alpha-D-glucose-1-phosphate. Cannot hydrolyze glucose-6-phosphate and fructose-6-phosphate. May be involved in the biosynthesis of a unique osmolyte, di-myo-inositol 1,1-phosphate.<ref>PMID:10747806</ref> <ref>PMID:11062561</ref> <ref>PMID:11940584</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Inositol monophosphatase 3D structures|Inositol monophosphatase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Arcfu]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Goldstein, R I]] | [[Category: Goldstein, R I]] | ||
[[Category: Roberts, M]] | [[Category: Roberts, M]] | ||
Revision as of 09:49, 4 December 2019
IMPase (AF2372) with 25 mM Asp
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