This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6b64
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==IMPase (AF2372) with 25 mM Asp== | ==IMPase (AF2372) with 25 mM Asp== | ||
| - | <StructureSection load='6b64' size='340' side='right' caption='[[6b64]], [[Resolution|resolution]] 2.60Å' scene=''> | + | <StructureSection load='6b64' size='340' side='right'caption='[[6b64]], [[Resolution|resolution]] 2.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6b64]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B64 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B64 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6b64]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arcfu Arcfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B64 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B64 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">suhB, AF_2372 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224325 ARCFU])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b64 OCA], [http://pdbe.org/6b64 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b64 RCSB], [http://www.ebi.ac.uk/pdbsum/6b64 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b64 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b64 OCA], [http://pdbe.org/6b64 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b64 RCSB], [http://www.ebi.ac.uk/pdbsum/6b64 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b64 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/BSUHB_ARCFU BSUHB_ARCFU]] Phosphatase with broad specificity; it can dephosphorylate fructose 1,6-bisphosphate, both D and L isomers of inositol-1-phosphate (I-1-P), 2'-AMP, pNPP, inositol-2-phosphate, beta-glycerol phosphate, and alpha-D-glucose-1-phosphate. Cannot hydrolyze glucose-6-phosphate and fructose-6-phosphate. May be involved in the biosynthesis of a unique osmolyte, di-myo-inositol 1,1-phosphate.<ref>PMID:10747806</ref> <ref>PMID:11062561</ref> <ref>PMID:11940584</ref> | [[http://www.uniprot.org/uniprot/BSUHB_ARCFU BSUHB_ARCFU]] Phosphatase with broad specificity; it can dephosphorylate fructose 1,6-bisphosphate, both D and L isomers of inositol-1-phosphate (I-1-P), 2'-AMP, pNPP, inositol-2-phosphate, beta-glycerol phosphate, and alpha-D-glucose-1-phosphate. Cannot hydrolyze glucose-6-phosphate and fructose-6-phosphate. May be involved in the biosynthesis of a unique osmolyte, di-myo-inositol 1,1-phosphate.<ref>PMID:10747806</ref> <ref>PMID:11062561</ref> <ref>PMID:11940584</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Inositol monophosphatase 3D structures|Inositol monophosphatase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Arcfu]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Goldstein, R I]] | [[Category: Goldstein, R I]] | ||
[[Category: Roberts, M]] | [[Category: Roberts, M]] | ||
Revision as of 09:49, 4 December 2019
IMPase (AF2372) with 25 mM Asp
| |||||||||||
