Receptor tyrosine kinases
From Proteopedia
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<StructureSection load='1dq8' size='490' side='right' caption='Solved Structures of Ephrin Type-A Receptors, [[1dq8]]' scene='Ephrin_Type-A_Receptor/Opening/1'> | <StructureSection load='1dq8' size='490' side='right' caption='Solved Structures of Ephrin Type-A Receptors, [[1dq8]]' scene='Ephrin_Type-A_Receptor/Opening/1'> | ||
| - | Receptor tyrosine kinases are part of the larger family of protein [[Tyrosine kinase|tyrosine kinases]]. They are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and [[Hormone|hormones]]. | + | Receptor tyrosine kinases (RTKs) are part of the larger family of protein [[Tyrosine kinase|tyrosine kinases]]. They are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and [[Hormone|hormones]]. Approximately 20 different RTK classes have been identified.<ref>PMID:26579483</ref> |
*[[Fibroblast growth factor receptor]] | *[[Fibroblast growth factor receptor]] | ||
*[[Ephrin receptor]] | *[[Ephrin receptor]] | ||
| - | *[[Epidermal Growth Factor Receptor]] | + | *RTK class I [[Epidermal Growth Factor Receptor]] |
| - | *[[Insulin receptor]] | + | *RTK class II [[Insulin receptor]] |
| - | *[[Vascular Endothelial Growth Factor Receptor]] | + | *RTK class IV [[Vascular Endothelial Growth Factor Receptor]] |
</StructureSection> | </StructureSection> | ||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 13:43, 10 December 2019
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References
- ↑ Segaliny AI, Tellez-Gabriel M, Heymann MF, Heymann D. Receptor tyrosine kinases: Characterisation, mechanism of action and therapeutic interests for bone cancers. J Bone Oncol. 2015 Jan 23;4(1):1-12. doi: 10.1016/j.jbo.2015.01.001. eCollection , 2015 Mar. PMID:26579483 doi:http://dx.doi.org/10.1016/j.jbo.2015.01.001
