Retinoic acid receptor
From Proteopedia
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| - | ==3D structures of retinoic acid receptor== | ||
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| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| - | *Retinoic acid receptor α | ||
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| - | **[[1dsz]] - hRAR LBD + hRXR LBD + DNA – human<br /> | ||
| - | **[[4dqm]] - hRAR LBD + NCOA-1 peptide<br /> | ||
| - | **[[5k13]] - hRAR LBD + inhibitor<br /> | ||
| - | **[[3kmr]] - hRAR LBD + NCOA-1 + agonist<br /> | ||
| - | **[[3kmz]] - hRAR LBD + corepressor + agonist<br /> | ||
| - | **[[3a9e]] - hRAR LBD + hRXR LBD + coactivator peptide<br /> | ||
| - | **[[1dkf]] – mRAR LBD + mRXR LBD – mouse<br /> | ||
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| - | *Retinoic acid receptor β | ||
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| - | **[[1hra]], [[1xap]] – hRAR DBD<br /> | ||
| - | **[[4dm8]] - hRAR LBD + NCOA-1 peptide + 9-''cis'' retinoic acid<br /> | ||
| - | **[[4dm6]], [[6ssq]] - hRAR LBD + NCOA-1 peptide<br /> | ||
| - | **[[4jyg]], [[4jyh]], [[4jyi]] - hRAR LBD + NCOA-1 + agonist<br /> | ||
| - | **[[1xdk]] - mRAR LBD + mRXR LBD + thyroid receptor associated protein | ||
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| - | *Retinoic acid receptor γ | ||
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| - | **[[1fcx]], [[1fcy]], [[1fcz]], [[1fd0]] - hRAR-1 LBD + retinoid<br /> | ||
| - | **[[5m24]] - hRAR-1 LBD (mutant) + retinoid<br /> | ||
| - | **[[1exa]], [[1exx]] – hRAR-2 LBD + retinoid<br /> | ||
| - | **[[2lbd]] – hRAR LBD + all-''trans'' retinoic acid<br /> | ||
| - | **[[3lbd]] – hRAR LBD + 9-''cis'' retinoic acid<br /> | ||
| - | **[[4lbd]], [[6fx0]] – hRAR LBD + agonist<br /> | ||
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| - | *Retinoic acid receptor | ||
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| - | **[[6eu9]] - RAR LBD + retinoid – ''Platynereis dumerilii''<br /> | ||
| - | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 12:25, 11 December 2019
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References
- ↑ Wu Q, Lin XF, Ye XF, Zhang B, Xie Z, Su WJ. Ubiquitinated or sumoylated retinoic acid receptor alpha determines its characteristic and interacting model with retinoid X receptor alpha in gastric and breast cancer cells. J Mol Endocrinol. 2004 Jun;32(3):595-613. PMID:15171703
- ↑ Sommer KM, Chen LI, Treuting PM, Smith LT, Swisshelm K. Elevated retinoic acid receptor beta(4) protein in human breast tumor cells with nuclear and cytoplasmic localization. Proc Natl Acad Sci U S A. 1999 Jul 20;96(15):8651-6. PMID:10411930
- ↑ Johansson HJ, Sanchez BC, Mundt F, Forshed J, Kovacs A, Panizza E, Hultin-Rosenberg L, Lundgren B, Martens U, Mathe G, Yakhini Z, Helou K, Krawiec K, Kanter L, Hjerpe A, Stal O, Linderholm BK, Lehtio J. Retinoic acid receptor alpha is associated with tamoxifen resistance in breast cancer. Nat Commun. 2013;4:2175. doi: 10.1038/ncomms3175. PMID:23868472 doi:http://dx.doi.org/10.1038/ncomms3175
- ↑ Khuri FR, Lotan R, Kemp BL, Lippman SM, Wu H, Feng L, Lee JJ, Cooksley CS, Parr B, Chang E, Walsh GL, Lee JS, Hong WK, Xu XC. Retinoic acid receptor-beta as a prognostic indicator in stage I non-small-cell lung cancer. J Clin Oncol. 2000 Aug;18(15):2798-804. PMID:10920126
- ↑ Soprano KJ, Soprano DR. Retinoic acid receptors and cancer. J Nutr. 2002 Dec;132(12):3809S-3813S. PMID:12468629
- ↑ Renaud JP, Rochel N, Ruff M, Vivat V, Chambon P, Gronemeyer H, Moras D. Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid. Nature. 1995 Dec 14;378(6558):681-9. PMID:7501014 doi:http://dx.doi.org/10.1038/378681a0
