6iws
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Solution structure of the J-domain of Tid1, a Mitochondrial Hsp40/DnaJ Protein== | |
| - | + | <StructureSection load='6iws' size='340' side='right'caption='[[6iws]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6iws]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IWS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IWS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6iws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iws OCA], [http://pdbe.org/6iws PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6iws RCSB], [http://www.ebi.ac.uk/pdbsum/6iws PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6iws ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: Kim, J | + | == Function == |
| - | [[Category: Won, H | + | [[http://www.uniprot.org/uniprot/DNJA3_HUMAN DNJA3_HUMAN]] Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma-mediated transcriptional activity. Isoform 2 may play a role in neuromuscular junction development as an effector of the MUSK signaling pathway. |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Jo, K S]] | ||
| + | [[Category: Kim, J H]] | ||
| + | [[Category: Sim, D W]] | ||
| + | [[Category: Won, H S]] | ||
| + | [[Category: Chaperone]] | ||
| + | [[Category: Dnaja3]] | ||
| + | [[Category: Hpd motif]] | ||
| + | [[Category: J-domain]] | ||
| + | [[Category: Mthsp40]] | ||
| + | [[Category: Solution structure]] | ||
| + | [[Category: Tid1]] | ||
Revision as of 15:03, 11 December 2019
Solution structure of the J-domain of Tid1, a Mitochondrial Hsp40/DnaJ Protein
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Categories: Large Structures | Jo, K S | Kim, J H | Sim, D W | Won, H S | Chaperone | Dnaja3 | Hpd motif | J-domain | Mthsp40 | Solution structure | Tid1
